5MC7
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2HF6
| Solution structure of human zeta-COP | Descriptor: | Coatomer subunit zeta-1 | Authors: | Yu, W, Jin, C, Xia, B. | Deposit date: | 2006-06-23 | Release date: | 2007-06-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats J.Mol.Biol., 386, 2009
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5MU7
| Crystal Structure of the beta/delta-COPI Core Complex | Descriptor: | Coatomer subunit beta, Coatomer subunit delta-like protein | Authors: | Kopp, J, Aderhold, P, Wieland, F, Sinning, I. | Deposit date: | 2017-01-12 | Release date: | 2017-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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4UQI
| AP2 controls clathrin polymerization with a membrane-activated switch | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... | Authors: | Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. | Deposit date: | 2014-06-23 | Release date: | 2014-07-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch. Science, 345, 2014
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8T1O
| AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Baker, R.W, Cannon, K.S, Reta, S. | Deposit date: | 2023-06-02 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins. J.Struct.Biol., 215, 2023
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2BP5
| MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG | Descriptor: | CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4 | Authors: | Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D. | Deposit date: | 2005-04-18 | Release date: | 2005-07-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors. J.Cell.Sci, 118, 2005
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4P6Z
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4HMY
| Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2012-10-18 | Release date: | 2013-03-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1. Cell(Cambridge,Mass.), 152, 2013
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6URI
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1W63
| AP1 clathrin adaptor core | Descriptor: | ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ... | Authors: | Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C. | Deposit date: | 2004-08-12 | Release date: | 2004-09-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal Structure of the Clathrin Adaptor Protein 1 Core Proc.Natl.Acad.Sci.USA, 101, 2004
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5A1X
| The structure of the COPI coat linkage III | Descriptor: | ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ... | Authors: | Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G. | Deposit date: | 2015-05-06 | Release date: | 2015-07-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly. Science, 349, 2015
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6YAF
| AP2 on a membrane containing tyrosine-based cargo peptide | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | Deposit date: | 2020-03-12 | Release date: | 2020-07-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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3TJZ
| Crystal Structure of Arf1 Bound to the gamma/zeta-COP Core Complex | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit gamma, Coatomer subunit zeta-1, ... | Authors: | Goldberg, J, Yu, X, Breitman, M. | Deposit date: | 2011-08-25 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A structure-based mechanism for arf1-dependent recruitment of coatomer to membranes. Cell(Cambridge,Mass.), 148, 2012
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4NEE
| crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef | Authors: | Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y. | Deposit date: | 2013-10-29 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8841 Å) | Cite: | How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. Elife, 3, 2014
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7UX3
| Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-05-04 | Release date: | 2023-05-10 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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5FPI
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7Z5C
| Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. | Deposit date: | 2022-03-09 | Release date: | 2022-05-11 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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6YAE
| AP2 core in physiological buffer | Descriptor: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. | Deposit date: | 2020-03-12 | Release date: | 2020-07-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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6YAH
| AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | Deposit date: | 2020-03-12 | Release date: | 2020-07-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (10.2 Å) | Cite: | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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2XA7
| AP2 clathrin adaptor core in active complex with cargo peptides | Descriptor: | ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ... | Authors: | Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J. | Deposit date: | 2010-03-29 | Release date: | 2010-07-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex Cell(Cambridge,Mass.), 141, 2010
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6CRI
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | Deposit date: | 2018-03-18 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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2VGL
| AP2 CLATHRIN ADAPTOR CORE | Descriptor: | ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ... | Authors: | Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R. | Deposit date: | 2007-11-14 | Release date: | 2007-12-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Architecture and Functional Model of the Endocytic Ap2 Complex Cell(Cambridge,Mass.), 109, 2002
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6CM9
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | Deposit date: | 2018-03-03 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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6DFF
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | Deposit date: | 2018-05-14 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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2JKT
| AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ... | Authors: | Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R. | Deposit date: | 2008-08-29 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex. Nature, 456, 2008
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