3ZDL
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![BU of 3zdl by Molmil](/molmil-images/mine/3zdl) | Vinculin head (1-258) in complex with a RIAM fragment | Descriptor: | AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN | Authors: | Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L. | Deposit date: | 2012-11-28 | Release date: | 2013-02-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover. J.Biol.Chem., 288, 2013
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1H6G
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![BU of 1h6g by Molmil](/molmil-images/mine/1h6g) | alpha-catenin M-domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ... | Authors: | Yang, J, Dokurno, P, Tonks, N.K, Barford, D. | Deposit date: | 2001-06-14 | Release date: | 2001-08-07 | Last modified: | 2016-02-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion. Embo J., 20, 2001
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1TR2
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![BU of 1tr2 by Molmil](/molmil-images/mine/1tr2) | Crystal structure of human full-length vinculin (residues 1-1066) | Descriptor: | VINCULIN ISOFORM 1 | Authors: | Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T. | Deposit date: | 2004-06-19 | Release date: | 2005-11-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of Human Vinculin Structure, 12, 2004
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5H5M
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![BU of 5h5m by Molmil](/molmil-images/mine/5h5m) | Crystal structure of HMP-1 M domain | Descriptor: | Alpha-catenin-like protein hmp-1 | Authors: | Kang, H, Bang, I, Weis, W.I, Choi, H.J. | Deposit date: | 2016-11-08 | Release date: | 2017-03-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin J. Biol. Chem., 292, 2017
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6FUY
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![BU of 6fuy by Molmil](/molmil-images/mine/6fuy) | Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066) | Descriptor: | CALCIUM ION, Vinculin | Authors: | Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B. | Deposit date: | 2018-02-28 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Conformational states during vinculin unlocking differentially regulate focal adhesion properties. Sci Rep, 8, 2018
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1L7C
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![BU of 1l7c by Molmil](/molmil-images/mine/1l7c) | alpha-catenin fragment, residues 385-651 | Descriptor: | Alpha E-catenin | Authors: | Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I. | Deposit date: | 2002-03-14 | Release date: | 2002-06-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J.Biol.Chem., 277, 2002
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5Y04
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![BU of 5y04 by Molmil](/molmil-images/mine/5y04) | |
6NR7
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![BU of 6nr7 by Molmil](/molmil-images/mine/6nr7) | Rerefinement of chicken vinculin | Descriptor: | (1R,2R,3S,4R,5R,6S)-4-{[(S)-[(2S)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-3,5,6-trihydroxycyclohexane-1,2-diyl bis[dihydrogen (phosphate)], PHOSPHATE ION, SULFATE ION, ... | Authors: | Stec, B. | Deposit date: | 2019-01-23 | Release date: | 2020-01-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Refined model of chicken vinculin suggests the mechanism of activation by helical super-bundle unfurling To be published
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6O3E
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![BU of 6o3e by Molmil](/molmil-images/mine/6o3e) | mouse aE-catenin 82-883 | Descriptor: | Catenin alpha-1 | Authors: | Pokutta, S, Weis, W.I. | Deposit date: | 2019-02-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.001 Å) | Cite: | Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling. Sci Rep, 9, 2019
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5XA5
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![BU of 5xa5 by Molmil](/molmil-images/mine/5xa5) | Crystal structure of HMP-1-HMP-2 complex | Descriptor: | Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2 | Authors: | Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J. | Deposit date: | 2017-03-11 | Release date: | 2017-08-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface. J.Biol.Chem., 292, 2017
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6BFI
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![BU of 6bfi by Molmil](/molmil-images/mine/6bfi) | |
5XFL
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![BU of 5xfl by Molmil](/molmil-images/mine/5xfl) | |
3S90
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![BU of 3s90 by Molmil](/molmil-images/mine/3s90) | Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546) | Descriptor: | Talin-1, Vinculin | Authors: | Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T. | Deposit date: | 2011-05-31 | Release date: | 2011-06-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin. Protein Sci., 20, 2011
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4ONS
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![BU of 4ons by Molmil](/molmil-images/mine/4ons) | Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation | Descriptor: | Catenin alpha-2, Catenin beta-1 | Authors: | Pokutta, S, Choi, H.-J, Ahlsen, G, Hansen, S.D, Weis, W.I. | Deposit date: | 2014-01-29 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation. J.Biol.Chem., 289, 2014
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6DUY
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![BU of 6duy by Molmil](/molmil-images/mine/6duy) | |
1ZW3
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![BU of 1zw3 by Molmil](/molmil-images/mine/1zw3) | Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652 | Descriptor: | Talin 1, Vinculin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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4K1O
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![BU of 4k1o by Molmil](/molmil-images/mine/4k1o) | |
1ZVZ
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![BU of 1zvz by Molmil](/molmil-images/mine/1zvz) | Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844 | Descriptor: | Talin 1, Vinculin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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1ZW2
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![BU of 1zw2 by Molmil](/molmil-images/mine/1zw2) | Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369 | Descriptor: | Vinculin, talin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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6DUW
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![BU of 6duw by Molmil](/molmil-images/mine/6duw) | |
3MYI
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![BU of 3myi by Molmil](/molmil-images/mine/3myi) | |
4K1N
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![BU of 4k1n by Molmil](/molmil-images/mine/4k1n) | |
4P9T
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![BU of 4p9t by Molmil](/molmil-images/mine/4p9t) | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin | Descriptor: | 1,2-ETHANEDIOL, Catenin alpha-2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Shibahara, T, Hirano, Y, Hakoshima, T. | Deposit date: | 2014-04-04 | Release date: | 2015-04-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin. Febs Lett., 589, 2015
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3TJ6
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![BU of 3tj6 by Molmil](/molmil-images/mine/3tj6) | human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii | Descriptor: | Antigenic heat-stable 120 kDa protein, Vinculin | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | Deposit date: | 2011-08-23 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J.Biol.Chem., 286, 2011
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6FQ4
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![BU of 6fq4 by Molmil](/molmil-images/mine/6fq4) | Structure of Chlamydial virulence factor TarP and vinculin head domain | Descriptor: | TarP-VBS1, Vinculin | Authors: | Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T. | Deposit date: | 2018-02-13 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex. FEBS Lett., 592, 2018
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