6JNA
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![BU of 6jna by Molmil](/molmil-images/mine/6jna) | Cryo-EM structure of glutamate dehydrogenase from Thermococcus profundus | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate dehydrogenase | Authors: | Oide, M, Kato, T, Oroguchi, T, Nakasako, M. | Deposit date: | 2019-03-14 | Release date: | 2020-02-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo-electron microscopy. Febs J., 287, 2020
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6UXE
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![BU of 6uxe by Molmil](/molmil-images/mine/6uxe) | Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2 | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | Authors: | Boniecki, M.T, Cygler, M. | Deposit date: | 2019-11-07 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
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6V1D
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![BU of 6v1d by Molmil](/molmil-images/mine/6v1d) | Crystal structure of human trefoil factor 1 | Descriptor: | Trefoil factor 1 | Authors: | Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D. | Deposit date: | 2019-11-20 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Trefoil factors share a lectin activity that defines their role in mucus. Nat Commun, 11, 2020
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7NZZ
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![BU of 7nzz by Molmil](/molmil-images/mine/7nzz) | |
7NS0
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![BU of 7ns0 by Molmil](/molmil-images/mine/7ns0) | Bacilladnavirus capsid structure | Descriptor: | Capsid protein VP2 | Authors: | Munke, A, Okamoto, K. | Deposit date: | 2021-03-05 | Release date: | 2022-07-20 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Primordial Capsid and Spooled ssDNA Genome Structures Unravel Ancestral Events of Eukaryotic Viruses. Mbio, 13, 2022
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6V0O
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![BU of 6v0o by Molmil](/molmil-images/mine/6v0o) | PRMT5 bound to the PBM peptide from pICln | Descriptor: | ACETYL GROUP, Methylosome protein 50, PBM peptide, ... | Authors: | McMillan, B.J, Raymond, D.D. | Deposit date: | 2019-11-19 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol.Cell, 81, 2021
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6YJG
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![BU of 6yjg by Molmil](/molmil-images/mine/6yjg) | Crystal structure of MINDY1 mutant-Y114F | Descriptor: | Ubiquitin carboxyl-terminal hydrolase MINDY1 | Authors: | Abdul Rehman, S.A, Kulathu, Y. | Deposit date: | 2020-04-03 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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6YJE
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![BU of 6yje by Molmil](/molmil-images/mine/6yje) | Plasmoodium vivax phosphoglycerate kinase bound to nitrofuran inhibitor from PEG3350 and ammonium acetate at pH 5.5 | Descriptor: | (2~{S})-2-(5-nitrofuran-2-yl)-2,3,5,6,7,8-hexahydro-1~{H}-[1]benzothiolo[2,3-d]pyrimidin-4-one, Phosphoglycerate kinase | Authors: | Blaszczyk, B.K, Hyvonen, M. | Deposit date: | 2020-04-03 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Phosphoglycerate Kinase as a potential target for antimalarial therapy to be published
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6P0S
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![BU of 6p0s by Molmil](/molmil-images/mine/6p0s) | Crystal structure of ternary DNA complex "FX2" containing E. coli Fis and phage lambda Xis | Descriptor: | DNA (27-MER), FX1-2, DNA-binding protein Fis, ... | Authors: | Hancock, S.P, Cascio, D, Johnson, R.C. | Deposit date: | 2019-05-17 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res., 47, 2019
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7O13
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![BU of 7o13 by Molmil](/molmil-images/mine/7o13) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-11-02 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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6P7T
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6YRA
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6YRU
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![BU of 6yru by Molmil](/molmil-images/mine/6yru) | Crystal structure of FAP in the dark at 100K | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID | Authors: | Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. | Deposit date: | 2020-04-20 | Release date: | 2021-04-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
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6VAJ
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![BU of 6vaj by Molmil](/molmil-images/mine/6vaj) | Crystal Structure Analysis of human PIN1 | Descriptor: | 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-12-17 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat.Chem.Biol., 17, 2021
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6PAB
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7OFG
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6V1C
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![BU of 6v1c by Molmil](/molmil-images/mine/6v1c) | Crystal structure of human trefoil factor 3 in complex with its cognate ligand | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose, Trefoil factor 3 | Authors: | Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D. | Deposit date: | 2019-11-20 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Trefoil factors share a lectin activity that defines their role in mucus. Nat Commun, 11, 2020
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6PA6
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7OJH
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![BU of 7ojh by Molmil](/molmil-images/mine/7ojh) | ABCG2 topotecan turnover-1 state | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | Deposit date: | 2021-05-15 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
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7OJI
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![BU of 7oji by Molmil](/molmil-images/mine/7oji) | ABCG2 topotecan turnover-2 state | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | Deposit date: | 2021-05-16 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
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6PAA
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7P5C
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![BU of 7p5c by Molmil](/molmil-images/mine/7p5c) | Cryo-EM structure of human TTYH3 in Ca2+ and GDN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 3 | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | Deposit date: | 2021-07-14 | Release date: | 2021-08-11 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. Nat Commun, 12, 2021
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6PHY
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![BU of 6phy by Molmil](/molmil-images/mine/6phy) | SpAga D472N structure in complex alpha 1,3 galactobiose | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... | Authors: | Pluvinage, B, Boraston, A.B. | Deposit date: | 2019-06-25 | Release date: | 2019-10-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
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6PL5
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![BU of 6pl5 by Molmil](/molmil-images/mine/6pl5) | Structural coordination of polymerization and crosslinking by a peptidoglycan synthase complex | Descriptor: | Penicillin-binding protein 2/cell division protein FtsI, Peptidoglycan glycosyltransferase RodA, Unknown peptide | Authors: | Sjodt, M, Rohs, P.D.A, Erlandson, S.C, Zheng, S, Rudner, D.Z, Bernhardt, T.G, Kruse, A.C. | Deposit date: | 2019-06-30 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nat Microbiol, 5, 2020
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6Z1Y
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![BU of 6z1y by Molmil](/molmil-images/mine/6z1y) | Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK) | Descriptor: | SODIUM ION, Trichobakin | Authors: | Boyko, K.M, Nikolaeva, A.Y, Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Popov, V.O, Usanov, S.A. | Deposit date: | 2020-05-14 | Release date: | 2020-05-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK) To Be Published
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