6YJE

Plasmoodium vivax phosphoglycerate kinase bound to nitrofuran inhibitor from PEG3350 and ammonium acetate at pH 5.5

Summary for 6YJE

• Entry DOI: 10.2210/pdb6yje/pdb
• Descriptor: Phosphoglycerate kinase, (2~{S})-2-(5-nitrofuran-2-yl)-2,3,5,6,7,8-hexahydro-1~{H}-[1]benzothiolo[2,3-d]pyrimidin-4-one (3 entities in total)
• Functional Keywords: phosphoglycerate kinase, metabolic enzyme, kinase, biosynthetic protein
• Biological source: Plasmodium vivax
• Total number of polymer chains: 1
• Total formula weight: 45518.36

Authors

Blaszczyk, B.K.,Hyvonen, M. (deposition date: 2020-04-03, release date: 2021-04-14, Last modification date: 2024-01-24)

• Primary citation: Bilsland, E.,Costa, F.,Blaszczyk, B.K.,Hyvonen, M.,Sunnerhagen, P.; Phosphoglycerate Kinase as a potential target for antimalarial therapy; to be published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)