7JYW
| Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope | Descriptor: | Beta-2-microglobulin, CALCIUM ION, MHC class I antigen, ... | Authors: | Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. | Deposit date: | 2020-09-01 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
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1CE6
| MHC CLASS I H-2DB COMPLEXED WITH A SENDAI VIRUS NUCLEOPROTEIN PEPTIDE | Descriptor: | PROTEIN (HUMAN BETA-2 MICROGLOBULIN), PROTEIN (MHC CLASS I H-2DB HEAVY CHAIN), PROTEIN (SENDAI VIRUS NUCLEOPROTEIN), ... | Authors: | Tormo, J, Jones, E.Y. | Deposit date: | 1999-03-17 | Release date: | 1999-03-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity. Immunity, 10, 1999
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1KCR
| CRYSTAL STRUCTURE OF ANTIBODY PC283 IN COMPLEX WITH PS1 PEPTIDE | Descriptor: | PC283 IMMUNOGLOBULIN, PS1 peptide | Authors: | Nair, D.T, Singh, K, Sahu, N, Rao, K.V.S, Salunke, D.M. | Deposit date: | 2001-11-11 | Release date: | 2002-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition. J.Immunol., 165, 2000
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6ILE
| CRYSTAL STRUCTURE OF A MUTANT PTAL-N*01:01 FOR 2.9 ANGSTROM, 52M 53D 54L DELETED | Descriptor: | Beta-2-microglobulin, HEV-1, MHC class I antigen | Authors: | Qu, Z.H, Zhang, N.Z, Xia, C. | Deposit date: | 2018-10-17 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding. J Immunol., 202, 2019
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4N0C
| 42F3 TCR pCPE3/H-2Ld complex | Descriptor: | 42F3 VmCh alpha, 42F3 VmCh beta, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-10-01 | Release date: | 2015-08-19 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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7FI6
| Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | Descriptor: | MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | Authors: | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | Deposit date: | 2021-07-30 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D to be published
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1IAI
| IDIOTYPE-ANTI-IDIOTYPE FAB COMPLEX | Descriptor: | ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A), IDIOTYPIC FAB 730.1.4 (IGG1) OF VIRUS NEUTRALIZING ANTIBODY | Authors: | Ban, N, Escobar, C, Garcia, R, Hasel, K, Day, J, Greenwood, A, McPherson, A. | Deposit date: | 1993-12-28 | Release date: | 1996-03-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of an idiotype-anti-idiotype Fab complex. Proc.Natl.Acad.Sci.USA, 91, 1994
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1PY4
| Beta2 microglobulin mutant H31Y displays hints for amyloid formations | Descriptor: | Beta-2-microglobulin precursor | Authors: | Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M. | Deposit date: | 2003-07-08 | Release date: | 2004-05-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation J.Mol.Biol., 335, 2004
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5DJA
| Fc Heterodimer Design 9.1 Y407M + T366I | Descriptor: | Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. | Deposit date: | 2015-09-01 | Release date: | 2016-03-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
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4NHU
| The M33 TCR p3M33l/H-2 Ld Complex | Descriptor: | 2C m33 alpha VmCh chimera, 2C m33 beta VmCh chimera, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-11-05 | Release date: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Interrogating TCR Signal Strength and Cross-Reactivity by Yeast Display of pMHC To be Published
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3ARF
| Ternary crystal structure of the mouse NKT TCR-CD1d-C20:2 | Descriptor: | (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Wun, K.S, Rossjohn, J. | Deposit date: | 2010-11-27 | Release date: | 2011-03-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
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3C8K
| The crystal structure of Ly49C bound to H-2Kb | Descriptor: | H-2 class I histocompatibility antigen, K-B alpha chain, Natural killer cell receptor Ly-49C, ... | Authors: | Deng, L, Mariuzza, R.A. | Deposit date: | 2008-02-12 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors. J.Biol.Chem., 283, 2008
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3RGV
| A single TCR bound to MHCI and MHC II reveals switchable TCR conformers | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | Authors: | Dai, S, Huseby, E, Scott-Browne, J, Rubtsova, K, Pinilla, C, Crawford, F, Marrack, P, Yin, L, Kappler, J.W. | Deposit date: | 2011-04-09 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers. Immunity, 35, 2011
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3CIQ
| A regulatable switch mediates self-association in an immunoglobulin fold | Descriptor: | Beta-2-microglobulin, COPPER (II) ION, L(+)-TARTARIC ACID | Authors: | Calabrese, M.F, Eakin, C.M, Wang, J.M, Miranker, A.D. | Deposit date: | 2008-03-11 | Release date: | 2008-09-02 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A regulatable switch mediates self-association in an immunoglobulin fold. Nat.Struct.Mol.Biol., 15, 2008
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2DBL
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8SHI
| Valpha3S1 Vbeta13S1 HLA C 0602 VRSRRCLRL | Descriptor: | Beta-2-microglobulin, MHC class I antigen (Fragment), T cell receptor alpha, ... | Authors: | Littler, D.R, Anand, S, Vivian, J.P, Rossjohn, J. | Deposit date: | 2023-04-14 | Release date: | 2023-06-28 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.90001726 Å) | Cite: | Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02. J.Biol.Chem., 299, 2023
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7RDV
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6KX9
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6E9G
| The crystal structure of bovine ultralong antibody BOV-2 | Descriptor: | Bovine ultralong antibody BOV-2 heavy chain, Bovine ultralong antibody BOV-2 light chain | Authors: | Dong, J, Crowe, J.E. | Deposit date: | 2018-08-01 | Release date: | 2019-05-01 | Method: | X-RAY DIFFRACTION (2.904 Å) | Cite: | Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol, 10, 2019
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5F1I
| MHC with 9-mer peptide | Descriptor: | 9-mer peptide, Beta2M, MHC class I DLA-88 | Authors: | Liu, J, Chai, Y, QI, J, Gao, G.F. | Deposit date: | 2015-11-30 | Release date: | 2016-11-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.904 Å) | Cite: | Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I J Immunol., 197, 2016
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4J4P
| The complex of human IgE-Fc with two bound Fab fragments | Descriptor: | Ig epsilon chain C region, Immunoglobulin G Fab Fragment Heavy Chain, Immunoglobulin G Fab Fragment Light Chain, ... | Authors: | Drinkwater, N, Sutton, B.J. | Deposit date: | 2013-02-07 | Release date: | 2014-03-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Human immunoglobulin E flexes between acutely bent and extended conformations. Nat.Struct.Mol.Biol., 21, 2014
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3QUX
| Structure of the mouse CD1d-alpha-C-GalCer-iNKT TCR complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-02-24 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
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3VWK
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6U2F
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5NME
| 868 TCR in complex with HLA A02 presenting SLYNTVATL | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | Deposit date: | 2017-04-05 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
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