4J4P

The complex of human IgE-Fc with two bound Fab fragments

Summary for 4J4P

Entry DOI	10.2210/pdb4j4p/pdb
Related	1LSO 2WQR 2Y7Q
Descriptor	Ig epsilon chain C region, Immunoglobulin G Fab Fragment Heavy Chain, Immunoglobulin G Fab Fragment Light Chain, ... (5 entities in total)
Functional Keywords	ig like domain, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	177746.06
Authors	Drinkwater, N.,Sutton, B.J. (deposition date: 2013-02-07, release date: 2014-03-12, Last modification date: 2020-07-29)
Primary citation	Drinkwater, N.,Cossins, B.P.,Keeble, A.H.,Wright, M.,Cain, K.,Hailu, H.,Oxbrow, A.,Delgado, J.,Shuttleworth, L.K.,Kao, M.W.,McDonnell, J.M.,Beavil, A.J.,Henry, A.J.,Sutton, B.J. Human immunoglobulin E flexes between acutely bent and extended conformations. Nat.Struct.Mol.Biol., 21:397-404, 2014 Cited by PubMed: 24632569 DOI: 10.1038/nsmb.2795 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.91 Å)

Structure validation