3CIQ
A regulatable switch mediates self-association in an immunoglobulin fold
Summary for 3CIQ
Entry DOI | 10.2210/pdb3ciq/pdb |
Related | 2f8o |
Descriptor | Beta-2-microglobulin, COPPER (II) ION, L(+)-TARTARIC ACID, ... (4 entities in total) |
Functional Keywords | class-1 mhc, amyloid, protein folding, dialysis-related amyloidosis, beta-2 microglobulin, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P61769 |
Total number of polymer chains | 12 |
Total formula weight | 143573.23 |
Authors | Calabrese, M.F.,Eakin, C.M.,Wang, J.M.,Miranker, A.D. (deposition date: 2008-03-11, release date: 2008-09-02, Last modification date: 2021-10-20) |
Primary citation | Calabrese, M.F.,Eakin, C.M.,Wang, J.M.,Miranker, A.D. A regulatable switch mediates self-association in an immunoglobulin fold. Nat.Struct.Mol.Biol., 15:965-971, 2008 Cited by PubMed: 19172750PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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