1LBG
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![BU of 1lbg by Molmil](/molmil-images/mine/1lbg) | LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR) | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | Deposit date: | 1996-01-03 | Release date: | 1996-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science, 271, 1996
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7WJE
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![BU of 7wje by Molmil](/molmil-images/mine/7wje) | Crystal structure of Lactococcus lactis subsp. cremoris GH31 alpha-1,3-glucosidase mutant D394A in complex with nigerotetraose | Descriptor: | 1,2-ETHANEDIOL, Alpha-xylosidase, alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose | Authors: | Ikegaya, M, Miyazaki, T. | Deposit date: | 2022-01-06 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of the strict specificity of a bacterial GH31 alpha-1,3-glucosidase for nigerooligosaccharides. J.Biol.Chem., 298, 2022
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7JLV
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![BU of 7jlv by Molmil](/molmil-images/mine/7jlv) | Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Disease resistance protein Roq1, MAGNESIUM ION | Authors: | Martin, R, Qi, T, Zhang, H, Lui, F, King, M, Toth, C, Nogales, E, Staskawicz, B.J. | Deposit date: | 2020-07-30 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ. Science, 370, 2020
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5OGA
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![BU of 5oga by Molmil](/molmil-images/mine/5oga) | Structure of minimal i-motif domain | Descriptor: | DNA (5'-D(*TP*(DCP)P*GP*TP*TP*CP*(DCP)P*GP*TP*TP*TP*TP*TP*CP*GP*TP*TP*CP*CP*GP*T)-3') | Authors: | Mir, B, Serrano, I, Buitrago, D, Orozco, M, Escaja, N, Gonzalez, C. | Deposit date: | 2017-07-12 | Release date: | 2017-11-29 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Prevalent Sequences in the Human Genome Can Form Mini i-Motif Structures at Physiological pH. J. Am. Chem. Soc., 139, 2017
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1LBH
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![BU of 1lbh by Molmil](/molmil-images/mine/1lbh) | INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | Deposit date: | 1996-02-17 | Release date: | 1996-07-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science, 271, 1996
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2ORQ
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![BU of 2orq by Molmil](/molmil-images/mine/2orq) | Murine Inducible Nitric Oxide Synthase Oxygenase Domain (DELTA 114) 4-(imidazol-1-yl)phenol and piperonylamine Complex | Descriptor: | 1-(1,3-BENZODIOXOL-5-YL)METHANAMINE, 4-(1H-IMIDAZOL-1-YL)PHENOL, Nitric oxide synthase, ... | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2007-02-04 | Release date: | 2007-04-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem., 50, 2007
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1GTK
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![BU of 1gtk by Molmil](/molmil-images/mine/1gtk) | Time-resolved and static-ensemble structural chemistry of hydroxymethylbilane synthase | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, PORPHOBILINOGEN DEAMINASE | Authors: | Helliwell, J.R, Nieh, Y.P, Raftery, J, Cassetta, A, Habash, J, Carr, P.D, Ursby, T, Wulff, M, Thompson, A.W, Niemann, A.C, Haedener, A. | Deposit date: | 2002-01-16 | Release date: | 2003-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Time-Resolved and Static-Ensemble Structural Chemistry of Hydroxymethylbilane Synthase Faraday Discuss., 122, 2003
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2ORP
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![BU of 2orp by Molmil](/molmil-images/mine/2orp) | Murine inducible nitric oxide synthase oxygenase domain (delta 114) 2-[4-(2-Imidazol-1-yl-6-methyl-pyrimidin-4-yl)-1-isobutyryl-piperazin-2-yl]-N-[2-(4-methoxy-phenyl)-ethyl]-acetamide complex | Descriptor: | 2-{(2R)-4-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-1-ISOBUTYRYLPIPERAZIN-2-YL}-N-[2-(4-METHOXYPHENYL)ETHYL]ACETAMIDE, PROTOPORPHYRIN IX CONTAINING FE, nitric oxide synthase, ... | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2007-02-04 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem., 50, 2007
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5OPL
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![BU of 5opl by Molmil](/molmil-images/mine/5opl) | Crystal structure of K25E cN-II mutant | Descriptor: | Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION | Authors: | Kugler, M, Hnizda, A, Pachl, P, Rezacova, P. | Deposit date: | 2017-08-10 | Release date: | 2018-06-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32, 2018
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5OPM
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![BU of 5opm by Molmil](/molmil-images/mine/5opm) | Crystal structure of D52N/R238W cN-II mutant bound to dATP and free phosphate | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ... | Authors: | Hnizda, A, Pachl, P, Rezacova, P. | Deposit date: | 2017-08-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32, 2018
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2ORR
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![BU of 2orr by Molmil](/molmil-images/mine/2orr) | Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]dioxol-5-yloxy)-2-(4-imidazol-1-yl-phenoxy)-pyrimidine Complex | Descriptor: | 1,2-ETHANEDIOL, 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE, Nitric oxide synthase, ... | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2007-02-04 | Release date: | 2007-04-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem., 50, 2007
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5OV5
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![BU of 5ov5 by Molmil](/molmil-images/mine/5ov5) | Bacillus megaterium porphobilinogen deaminase D82E mutant | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Guo, J, Erskine, P, Coker, A.R, Wood, S.P, Cooper, J.B. | Deposit date: | 2017-08-28 | Release date: | 2017-09-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Acta Crystallogr F Struct Biol Commun, 73, 2017
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1BCS
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![BU of 1bcs by Molmil](/molmil-images/mine/1bcs) | COMPLEX OF THE WHEAT SERINE CARBOXYPEPTIDASE, CPDW-II, WITH THE MICROBIAL PEPTIDE ALDEHYDE INHIBITOR, CHYMOSTATIN, AND ARGININE AT 100 DEGREES KELVIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Bullock, T.L, Remington, S.J. | Deposit date: | 1995-11-03 | Release date: | 1996-03-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Peptide aldehyde complexes with wheat serine carboxypeptidase II: implications for the catalytic mechanism and substrate specificity. J.Mol.Biol., 255, 1996
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1ADC
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![BU of 1adc by Molmil](/molmil-images/mine/1adc) | CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGUES BOUND TO ALCOHOL DEHYDROGENASE: SPECIFICITY AND SUBSTRATE BINDING IN TWO TERNARY COMPLEXES | Descriptor: | 5-BETA-D-RIBOFURANOSYLPICOLINAMIDE ADENINE-DINUCLEOTIDE, ALCOHOL DEHYDROGENASE, ETHANOL, ... | Authors: | Li, H, Hallows, W.A, Punzi, J.S, Pankiewicz, K.W, Watanabe, K.A, Goldstein, B.M. | Deposit date: | 1993-12-13 | Release date: | 1995-06-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystallographic studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate binding in two ternary complexes. Biochemistry, 33, 1994
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5OIY
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![BU of 5oiy by Molmil](/molmil-images/mine/5oiy) | Structure of the HMPV P oligomerization domain at 2.2 A | Descriptor: | Phosphoprotein | Authors: | Renner, M, Paesen, G.C, Grison, C.M, Granier, S, Grimes, J.M, Leyrat, C. | Deposit date: | 2017-07-19 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering. Sci Rep, 7, 2017
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7WZX
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![BU of 7wzx by Molmil](/molmil-images/mine/7wzx) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one, 4Fe-4S cluster-binding domain-containing protein, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2022-02-19 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.980013 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7WZV
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![BU of 7wzv by Molmil](/molmil-images/mine/7wzv) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol, 1,2-ETHANEDIOL, 4Fe-4S cluster-binding domain-containing protein, ... | Authors: | Zhou, J.H, Hou, X.L. | Deposit date: | 2022-02-19 | Release date: | 2022-12-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.899313 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7X0B
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![BU of 7x0b by Molmil](/molmil-images/mine/7x0b) | The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | 4Fe-4S cluster-binding domain-containing protein, CHLORIDE ION, GLYCEROL, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2022-02-21 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.02027535 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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5OIX
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![BU of 5oix by Molmil](/molmil-images/mine/5oix) | Structure of the HMPV P oligomerization domain at 1.6 A | Descriptor: | GLYCEROL, Phosphoprotein | Authors: | Renner, M, Paesen, G.C, Grison, C.M, Granier, S, Grimes, J.M, Leyrat, C. | Deposit date: | 2017-07-19 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering. Sci Rep, 7, 2017
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7X0Y
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![BU of 7x0y by Molmil](/molmil-images/mine/7x0y) | |
5OLK
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![BU of 5olk by Molmil](/molmil-images/mine/5olk) | Crystal structure of the ATP-cone-containing NrdB from Leeuwenhoekiella blandensis | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | Authors: | Hasan, M, Grinberg, A.R, Sjoberg, B.M, Logan, D.T. | Deposit date: | 2017-07-28 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit. Elife, 7, 2018
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1CDD
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![BU of 1cdd by Molmil](/molmil-images/mine/1cdd) | STRUCTURES OF APO AND COMPLEXED ESCHERICHIA COLI GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | Descriptor: | PHOSPHATE ION, PHOSPHORIBOSYL-GLYCINAMIDE FORMYLTRANSFERASE | Authors: | Almassy, R.J, Janson, C.A, Kan, C.-C, Hostomska, Z. | Deposit date: | 1992-05-15 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of apo and complexed Escherichia coli glycinamide ribonucleotide transformylase. Proc.Natl.Acad.Sci.USA, 89, 1992
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5OPO
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![BU of 5opo by Molmil](/molmil-images/mine/5opo) | Crystal structure of R238G cN-II mutant | Descriptor: | Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION | Authors: | Hnizda, A, Pachl, P, Rezacova, P. | Deposit date: | 2017-08-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32, 2018
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1HSX
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![BU of 1hsx by Molmil](/molmil-images/mine/1hsx) | |
5OPP
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![BU of 5opp by Molmil](/molmil-images/mine/5opp) | Crystal structure of S408R cN-II mutant | Descriptor: | BROMIDE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ... | Authors: | Hnizda, A, Pachl, P, Rezacova, P. | Deposit date: | 2017-08-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32, 2018
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