2ORQ
Murine Inducible Nitric Oxide Synthase Oxygenase Domain (DELTA 114) 4-(imidazol-1-yl)phenol and piperonylamine Complex
Summary for 2ORQ
Entry DOI | 10.2210/pdb2orq/pdb |
Related | 1DD7 1NOC 1NOD 1NOS 1NSI 2NOS 2ORO 2ORP 2ORR 2ORS 2ORT |
Descriptor | Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, 4-(1H-IMIDAZOL-1-YL)PHENOL, ... (5 entities in total) |
Functional Keywords | nitric oxide, l-arginine monooxygenase, heme, dimerization, inhibitor, nos, oxidoreductase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 1 |
Total formula weight | 46198.20 |
Authors | Adler, M.,Whitlow, M. (deposition date: 2007-02-04, release date: 2007-04-17, Last modification date: 2024-02-21) |
Primary citation | Davey, D.D.,Adler, M.,Arnaia, D.,Eagen, K.,Erickson, S.,Guilford, W.,Kenrick, M.,Morrissey, M.M.,Ohimeyer, M.,Pan, G.,Paradkar, V.M.,Parkinson, J.,Polokoff, M.,Salonz, K.,Santos, C.,Subramanyam, B.,Vergona, R.,Wei, R.G.,Whitlow, M.,Ye, B.,Zhao, Z.S.,Devlin, J.J.,Phillips, G. Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem., 50:1146-1157, 2007 Cited by PubMed: 17315988DOI: 10.1021/jm061319i PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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