6BYH
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6WRZ
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![BU of 6wrz by Molmil](/molmil-images/mine/6wrz) | Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove. | Descriptor: | 2'-O-methyltransferase, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-04-30 | Release date: | 2020-05-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design. Sci.Signal., 13, 2020
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8SZK
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5MM1
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![BU of 5mm1 by Molmil](/molmil-images/mine/5mm1) | Dolichyl phosphate mannose synthase in complex with GDP and dolichyl phosphate mannose | Descriptor: | Dolichol monophosphate mannose synthase, GUANOSINE-5'-DIPHOSPHATE, dolichyl phosphate mannose | Authors: | Gandini, R, Reichenbach, T, Tan, T.C, Divne, C. | Deposit date: | 2016-12-08 | Release date: | 2017-08-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for dolichylphosphate mannose biosynthesis. Nat Commun, 8, 2017
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5ME5
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![BU of 5me5 by Molmil](/molmil-images/mine/5me5) | Crystal Structure of eiF4E from C. melo bound to a eIF4G peptide | Descriptor: | Eukaryotic transcription initiation factor 4E, SULFATE ION, eIF4G | Authors: | Querol-Audi, J, Silva, C, Miras, M, Truniger, V, Aranda-Regules, M, Verdaguer, N. | Deposit date: | 2016-11-14 | Release date: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation. Plant Physiol., 174, 2017
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5ME9
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![BU of 5me9 by Molmil](/molmil-images/mine/5me9) | Crystal structure of yeast Cdt1 (N terminal and middle domain), form 1. | Descriptor: | Cell division cycle protein CDT1, GLYCEROL, SULFATE ION | Authors: | Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. | Deposit date: | 2016-11-14 | Release date: | 2017-05-17 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
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7LUR
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6TMH
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![BU of 6tmh by Molmil](/molmil-images/mine/6tmh) | Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, OSCP/F1/c-ring model | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha,subunit alpha, ... | Authors: | Muhleip, A, Kock Flygaard, R, Amunts, A. | Deposit date: | 2019-12-04 | Release date: | 2020-12-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nat Commun, 12, 2021
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6TEH
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![BU of 6teh by Molmil](/molmil-images/mine/6teh) | Baseplate of native GTA particle computed with C3 symmetry | Descriptor: | IRON/SULFUR CLUSTER, Putative gene transfer agent protein | Authors: | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | Deposit date: | 2019-11-12 | Release date: | 2020-07-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
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6S2E
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6S2F
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6BX5
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7LSW
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![BU of 7lsw by Molmil](/molmil-images/mine/7lsw) | Structure of Full Beta-Hairpin LIR from FNIP2 Bound to GABARAP | Descriptor: | Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION | Authors: | Appleton, B.A. | Deposit date: | 2021-02-18 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. Sci Adv, 7, 2021
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1GUT
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5L0F
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6O0O
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![BU of 6o0o by Molmil](/molmil-images/mine/6o0o) | crystal structure of BCL-2 G101V mutation with S55746 | Descriptor: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2, ~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide | Authors: | Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. | Deposit date: | 2019-02-17 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. Nat Commun, 10, 2019
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6RJF
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![BU of 6rjf by Molmil](/molmil-images/mine/6rjf) | Echovirus 1 intact particle | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Domanska, A, Ruokolainen, V.P, Pelliccia, M, Laajala, M.A, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2019-04-26 | Release date: | 2019-06-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation. J.Virol., 93, 2019
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5KLC
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![BU of 5klc by Molmil](/molmil-images/mine/5klc) | Structure of CBM_E1, a novel carbohydrate-binding module found by sugar cane soil metagenome | Descriptor: | Carbohydrate binding module E1 | Authors: | Liberato, M.V, Campos, B.M, Zeri, A.C.M, Squina, F.M. | Deposit date: | 2016-06-24 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties. J.Biol.Chem., 291, 2016
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6IAA
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![BU of 6iaa by Molmil](/molmil-images/mine/6iaa) | hRobo2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Barak, R, Isupov, N.M, Opatowsky, Y. | Deposit date: | 2018-11-26 | Release date: | 2019-03-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural Principles in Robo Activation and Auto-inhibition. Cell, 177, 2019
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5N72
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5KMX
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![BU of 5kmx by Molmil](/molmil-images/mine/5kmx) | Structure of Trypanosoma congolense Insect Stage Antigen | Descriptor: | GLYCEROL, Putative uncharacterized protein TCIL3000_10_9440, SULFATE ION | Authors: | Ramaswamy, R, Parker, M.L, Boulanger, M.J. | Deposit date: | 2016-06-27 | Release date: | 2017-07-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.452 Å) | Cite: | Structural characterization reveals a novel bilobed architecture for the ectodomains of insect stage expressed Trypanosoma brucei PSSA-2 and Trypanosoma congolense ISA. Protein Sci., 25, 2016
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5KK4
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![BU of 5kk4 by Molmil](/molmil-images/mine/5kk4) | Crystal Structure of the Plant Defensin NsD7 bound to Phosphatidic Acid | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Kvansakul, M, Hulett, M.D, Lay, F.T. | Deposit date: | 2016-06-21 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization. Proc.Natl.Acad.Sci.USA, 113, 2016
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6NW5
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7M8I
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![BU of 7m8i by Molmil](/molmil-images/mine/7m8i) | Human CYP11B2 and human adrenodoxin in complex with fadrozole | Descriptor: | 4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile, Adrenodoxin, Cytochrome P450 11B2, ... | Authors: | Scott, E.E, Brixius-Anderko, S. | Deposit date: | 2021-03-29 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin. J.Biol.Chem., 296, 2021
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6RUS
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![BU of 6rus by Molmil](/molmil-images/mine/6rus) | Structure of a functional properdin monomer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-05-29 | Release date: | 2019-08-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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