7LUR

Stable Effector Functionless 2 (SEFL2) IgG1 Fc Scaffold Bound to a Minimized Version of the B-domain (Mini-Z) from Protein A Called Z34C

Summary for 7LUR

• Entry DOI: 10.2210/pdb7lur/pdb
• Descriptor: Immunoglobulin heavy constant gamma 1, Mini Z domain (3 entities in total)
• Functional Keywords: fragment crystallizable, fc, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 59393.22

Authors

Sudom, A.,Garces, F.,Wang, Z. (deposition date: 2021-02-23, release date: 2021-09-15, Last modification date: 2023-10-18)

• Primary citation: Estes, B.,Sudom, A.,Gong, D.,Whittington, D.A.,Li, V.,Mohr, C.,Li, D.,Riley, T.P.,Shi, S.D.,Zhang, J.,Garces, F.,Wang, Z.; Next generation Fc scaffold for multispecific antibodies.; Iscience, 24:103447-103447, 2021; PubMed: 34877503; DOI: 10.1016/j.isci.2021.103447

Experimental method

X-RAY DIFFRACTION (1.95 Å)