6S2F
Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon (Class 2)
Summary for 6S2F
| Entry DOI | 10.2210/pdb6s2f/pdb |
| EMDB information | 10088 10089 |
| Descriptor | DNA polymerase epsilon catalytic subunit A, Chromosome transmission fidelity protein 8, Chromosome transmission fidelity protein 18, ... (5 entities in total) |
| Functional Keywords | dna polymerase, pcna loader, protein complex, replication |
| Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
| Total number of polymer chains | 4 |
| Total formula weight | 203931.69 |
| Authors | Grabarczyk, D.B.,Song, B. (deposition date: 2019-06-20, release date: 2020-07-08, Last modification date: 2021-01-20) |
| Primary citation | Stokes, K.,Winczura, A.,Song, B.,Piccoli, G.,Grabarczyk, D.B. Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48:8128-8145, 2020 Cited by PubMed: 32585006DOI: 10.1093/nar/gkaa541 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.8 Å) |
Structure validation
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