6S2F

Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon (Class 2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0008622	cellular_component	epsilon DNA polymerase complex
B	0000775	cellular_component	chromosome, centromeric region
B	0000785	cellular_component	chromatin
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0006260	biological_process	DNA replication
B	0007064	biological_process	mitotic sister chromatid cohesion
B	0031390	cellular_component	Ctf18 RFC-like complex
B	0034088	biological_process	maintenance of mitotic sister chromatid cohesion
B	0034398	biological_process	telomere tethering at nuclear periphery
B	0035753	biological_process	maintenance of DNA trinucleotide repeats
D	0003674	molecular_function	molecular_function
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006260	biological_process	DNA replication
D	0007064	biological_process	mitotic sister chromatid cohesion
D	0031390	cellular_component	Ctf18 RFC-like complex
D	0034398	biological_process	telomere tethering at nuclear periphery
D	0035753	biological_process	maintenance of DNA trinucleotide repeats

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SF4 A 1401

Chain	Residue
A	ASP664
A	CYS665
A	CYS668
A	ASP669
A	CYS677
A	ALA678
A	CYS763
A	ARG765

---