8SZK

The cryo-EM structure of PPP2R5A/HIV-1 Vif/CBFb/EloB/EloC complex

Summary for 8SZK

• Entry DOI: 10.2210/pdb8szk/pdb
• EMDB information: 40919
• Descriptor: Elongin-B, Elongin-C, Core-binding factor subunit beta, ... (5 entities in total)
• Functional Keywords: hiv vif, cul5 e3 ligase, ppp2r5a, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 124884.19

Authors

Hu, Y.,Xiong, Y. (deposition date: 2023-05-30, release date: 2024-06-05)

• Primary citation: Hu, Y.,Delviks-Frankenberry, K.A.,Wu, C.,Arizaga, F.,Pathak, V.K.,Xiong, Y.; Structural insights into PPP2R5A degradation by HIV-1 Vif.; Nat.Struct.Mol.Biol., 2024; PubMed: 38789685; DOI: 10.1038/s41594-024-01314-6

Experimental method

ELECTRON MICROSCOPY (3.58 Å)