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3JYH
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BU of 3jyh by Molmil
Human dipeptidyl peptidase DPP7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl-peptidase 2, ...
Authors:Dobrovetsky, E, Dong, A, Seitova, A, Crombett, L, Paganon, S, Cossar, D, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Hassel, A, Shewchuk, L, Bochkarev, A, Structural Genomics Consortium (SGC)
Deposit date:2009-09-21
Release date:2009-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Human dipeptidyl peptidase DPP7
To be Published
4V7T
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BU of 4v7t by Molmil
Crystal structure of the E. coli ribosome bound to chloramphenicol.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
Deposit date:2010-08-14
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1942 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
8CML
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BU of 8cml by Molmil
Cryo-EM structure of complement C5 in complex with nanobodies UNbC5-1 and UNbC5-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ...
Authors:De la O Becerra, K.I, Gros, P.
Deposit date:2023-02-20
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies.
J.Biol.Chem., 299, 2023
3K2K
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BU of 3k2k by Molmil
Crystal structure of putative carboxypeptidase (YP_103406.1) from BURKHOLDERIA MALLEI ATCC 23344 at 2.49 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, putative carboxypeptidase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-09-30
Release date:2009-11-03
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal structure of putative carboxypeptidase (YP_103406.1) from BURKHOLDERIA MALLEI ATCC 23344 at 2.49 A resolution
To be published
3JAR
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BU of 3jar by Molmil
Cryo-EM structure of GDP-microtubule co-polymerized with EB3
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2015-06-19
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3K69
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BU of 3k69 by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE TRANSCRIPTIONAL REGULATOR (LP_0360) FROM LACTOBACILLUS PLANTARUM AT 1.95 A RESOLUTION
Descriptor: DIMETHYL SULFOXIDE, Putative transcription regulator
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-10-08
Release date:2009-11-03
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Putative transcriptional regulator (NP_784167.1) from LACTOBACILLUS PLANTARUM at 1.95 A resolution
To be published
5J2K
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BU of 5j2k by Molmil
Ternary complex crystal structure of DNA polymerase Beta with T:T mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
3K6V
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BU of 3k6v by Molmil
M. acetivorans Molybdate-Binding Protein (ModA) in Citrate-Bound Open Form
Descriptor: CITRIC ACID, Solute-binding protein MA_0280
Authors:Chan, S, Giuroiu, I, Chernishof, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J.
Deposit date:2009-10-09
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans
Acta Crystallogr.,Sect.F, 66, 2010
3JWJ
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BU of 3jwj by Molmil
Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-CN
Descriptor: Hen1
Authors:Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
Deposit date:2009-09-18
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JY9
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BU of 3jy9 by Molmil
Janus Kinase 2 Inhibitors
Descriptor: (3S)-3-(4-hydroxyphenyl)-1,5-dihydro-1,5,12-triazabenzo[4,5]cycloocta[1,2,3-cd]inden-4(3H)-one, SODIUM ION, Tyrosine-protein kinase JAK2
Authors:Zuccola, H.J, Ledeboer, M.W, Pierce, A.C.
Deposit date:2009-09-21
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole.
J.Med.Chem., 52, 2009
3K03
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BU of 3k03 by Molmil
Crystal Structure of CNG mimicking NaK mutant, NaK-DTPP, K+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein NaK
Authors:Jiang, Y, Derebe, M.G.
Deposit date:2009-09-24
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Proc.Natl.Acad.Sci.USA, 108, 2011
4V4J
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BU of 4v4j by Molmil
Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome.
Descriptor: 16S RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
Authors:Korostelev, A, Trakhanov, S, Asahara, H, Laurberg, M, Noller, H.F.
Deposit date:2007-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3C45
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BU of 3c45 by Molmil
Human dipeptidyl peptidase IV/CD26 in complex with a fluoroolefin inhibitor
Descriptor: (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Scapin, G, Edmondson, S.D, Weber, A.E.
Deposit date:2008-01-29
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
4V9H
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BU of 4v9h by Molmil
Crystal structure of the ribosome bound to elongation factor G in the guanosine triphosphatase state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V.
Deposit date:2013-03-25
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.857 Å)
Cite:Elongation factor G bound to the ribosome in an intermediate state of translocation.
Science, 340, 2013
4V9R
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BU of 4v9r by Molmil
Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
Deposit date:2013-12-05
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
3JRN
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BU of 3jrn by Molmil
Crystal structure of TIR domain from Arabidopsis Thaliana
Descriptor: ARSENIC, AT1G72930 protein
Authors:Chan, S.L, Mukasa, T, Santelli, E, Low, L.Y, Pascual, J.
Deposit date:2009-09-08
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants.
Protein Sci., 19, 2009
3K92
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BU of 3k92 by Molmil
Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG
Descriptor: DI(HYDROXYETHYL)ETHER, NAD-specific glutamate dehydrogenase
Authors:Gunka, K, Newman, J.A, Commichau, F.M, Herzberg, C, Rodrigues, C, Hewitt, L, Lewis, R.J, Stulke, J.
Deposit date:2009-10-15
Release date:2010-06-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties
J.Mol.Biol., 400, 2010
4W7N
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BU of 4w7n by Molmil
CRYSTAL STRUCTURE OF A DECOLORIZING PEROXIDASE (DYP) FROM AURICULARIA AURICULA-JUDAE. Y147S AND W377S DOUBLE MUTANT
Descriptor: Dye-decolorizing peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Medrano, F.J, Romero, A.
Deposit date:2014-08-22
Release date:2015-03-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Catalytic surface radical in dye-decolorizing peroxidase: a computational, spectroscopic and site-directed mutagenesis study.
Biochem.J., 466, 2015
3JSO
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BU of 3jso by Molmil
Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex
Descriptor: DNA (5'-D(*TP*AP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*A)-3'), LexA repressor
Authors:Zhang, A.P.P, Pigli, Y.Z, Rice, P.A.
Deposit date:2009-09-10
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of the LexA-DNA complex and implications for SOS box measurement.
Nature, 466, 2010
3JTC
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BU of 3jtc by Molmil
Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ...
Authors:Bajaj, S.P, Vadivel, K, Agah, S, Cascio, D, Krishnaswamy, S, Esmon, C, Padmanabhan, K.
Deposit date:2009-09-11
Release date:2011-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium.
J.Mol.Biol., 425, 2013
3JUI
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BU of 3jui by Molmil
Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
Descriptor: GLYCEROL, Translation initiation factor eIF-2B subunit epsilon
Authors:Wei, J, Xu, H, Zhang, C, Wang, M, Gao, F, Gong, W.
Deposit date:2009-09-15
Release date:2009-10-06
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
To be published
3JV3
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BU of 3jv3 by Molmil
Structure of SH3E-DH unit of murine intersectin-1L
Descriptor: Intersectin-1
Authors:Ahmad, K.F.
Deposit date:2009-09-15
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin.
Plos One, 5, 2010
5J0P
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BU of 5j0p by Molmil
Binary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0S
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BU of 5j0s by Molmil
Binary complex crystal structure of DNA polymerase Beta with C:T mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
3K3F
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BU of 3k3f by Molmil
Crystal Structure of the Urea Transporter from Desulfovibrio Vulgaris
Descriptor: GOLD ION, Urea transporter
Authors:Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-10-02
Release date:2009-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a bacterial homologue of the kidney urea transporter.
Nature, 462, 2009

223532

數據於2024-08-07公開中

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