2EE2
 
 | | Solution structures of the fn3 domain of human contactin 1 | | Descriptor: | Contactin-1 | | Authors: | Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-15 | | Release date: | 2007-08-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the fn3 domain of human contactin 1
To be Published
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2CK2
 | | Structure of core-swapped mutant of fibronectin | | Descriptor: | ACETYL GROUP, HUMAN FIBRONECTIN | | Authors: | Ng, S.P, Billings, K.S, Ohashi, T, Allen, M.D, Best, R.B, Randles, L.G, Erickson, H.P, Clarke, J. | | Deposit date: | 2006-04-10 | | Release date: | 2007-04-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Designing an Extracellular Matrix Protein with Enhanced Mechanical Stability
Proc.Natl.Acad.Sci.USA, 104, 2007
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2FNB
 | | NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES | | Descriptor: | PROTEIN (FIBRONECTIN) | | Authors: | Fattorusso, R, Pellecchia, M, Viti, F, Neri, P, Neri, D, Wuthrich, K. | | Deposit date: | 1998-12-16 | | Release date: | 1998-12-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the human oncofoetal fibronectin ED-B domain, a specific marker for angiogenesis.
Structure Fold.Des., 7, 1999
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2GEE
 | | Crystal Structure of Human Type III Fibronectin Extradomain B and Domain 8 | | Descriptor: | hypothetical protein | | Authors: | Bencharit, S, Cui, C.B, Siddiqui, A, Howard-Williams, E.L, Aukhil, I. | | Deposit date: | 2006-03-19 | | Release date: | 2006-10-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural insights into fibronectin type III domain-mediated signaling.
J.Mol.Biol., 367, 2007
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2H41
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2HA1
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2HAZ
 | | Crystal structure of the first fibronectin domain of human NCAM1 | | Descriptor: | Neural cell adhesion molecule 1, SODIUM ION | | Authors: | Sekulic, N, Lavie, A. | | Deposit date: | 2006-06-13 | | Release date: | 2006-10-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A novel alpha-helix in the first fibronectin type III repeat of the neural cell adhesion molecule is critical for N-glycan polysialylation.
J.Biol.Chem., 281, 2006
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2H45
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2DM4
 | | Solution structure of the second fn3 domain of human sorLA/LR11 | | Descriptor: | Sortilin-related receptor | | Authors: | Nagashima, T, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-20 | | Release date: | 2006-10-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the second fn3 domain of human sorLA/LR11
To be Published
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2ED7
 | | Solution structure of the first fibronectin type III domain of human Netrin receptor DCC | | Descriptor: | Netrin receptor DCC | | Authors: | Tochio, N, Koshiba, S, Tomizawa, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-14 | | Release date: | 2008-02-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first fibronectin type III domain of human Netrin receptor DCC
To be Published
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2DN7
 | | Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F | | Descriptor: | Receptor-type tyrosine-protein phosphatase F | | Authors: | Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-25 | | Release date: | 2006-10-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F
To be Published
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2IBB
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9BA4
 | | Full-length cross-linked Contactin 2 (CNTN2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2 | | Authors: | Liu, J.L, Fan, S.F, Ren, G.R, Rudenko, G.R. | | Deposit date: | 2024-04-03 | | Release date: | 2024-07-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Molecular mechanism of contactin 2 homophilic interaction.
Structure, 2024
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6NAJ
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4URT
 | | The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R. | | Deposit date: | 2014-07-02 | | Release date: | 2014-09-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue
Neuron, 83, 2014
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4GH7
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6SOF
 | | human insulin receptor ectodomain bound by 4 insulin | | Descriptor: | Insulin, Insulin receptor | | Authors: | Gutmann, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | | Deposit date: | 2019-08-29 | | Release date: | 2019-11-13 | | Last modified: | 2020-05-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.
J.Cell Biol., 219, 2020
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3N1G
 | | Crystal structure of DhhN bound to BOCFn3 | | Descriptor: | Brother of CDO, CALCIUM ION, Desert hedgehog protein, ... | | Authors: | Kavran, J.M, Leahy, D.J. | | Deposit date: | 2010-05-15 | | Release date: | 2010-06-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
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3N1P
 | | Crystal Structure of IhhN bound to BOCFn3 | | Descriptor: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | | Authors: | Kavran, J.M, Leahy, D.J. | | Deposit date: | 2010-05-16 | | Release date: | 2010-06-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
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3EW3
 | | the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor | | Descriptor: | Prolactin, Prolactin receptor | | Authors: | Broutin, I, Jomain, J.B, England, P, Goffin, V. | | Deposit date: | 2008-10-14 | | Release date: | 2009-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.
J.Biol.Chem., 285, 2010
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4M4P
 | | Crystal structure of EPHA4 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4 | | Authors: | Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B. | | Deposit date: | 2013-08-07 | | Release date: | 2013-10-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.081 Å) | | Cite: | Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1KF9
 | | PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR | | Descriptor: | EXTRACELLULAR DOMAIN HUMAN GROWTH HORMONE RECEPTOR (1-238), PHAGE DISPLAY DERIVED VARIANT HUMAN GROWTH HORMONE | | Authors: | Schiffer, C.A, Ultsch, M, Walsh, S, Somers, W, De Vos, A.M, Kossiakoff, A.A. | | Deposit date: | 2001-11-19 | | Release date: | 2002-11-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of a Phage Display Derived Variant of Human Growth Hormone Complexed to Two Copies of the Extracellular Domain of its Receptor: Evidence for Strong Structural Coupling between Receptor Binding Sites
J.Mol.Biol., 316, 2002
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5XWT
 | | Crystal structure of PTPdelta Ig1-Fn1 in complex with SALM5 LRR-Ig | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S. | | Deposit date: | 2017-06-30 | | Release date: | 2018-06-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (4.178 Å) | | Cite: | Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation.
Nat Commun, 9, 2018
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3NPZ
 | | Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL) | | Descriptor: | Prolactin, Prolactin receptor | | Authors: | Van Agthoven, J, England, P, Goffin, V, Broutin, I. | | Deposit date: | 2010-06-29 | | Release date: | 2010-10-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
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8X81
 | | Structure of leptin-LepR trimer with a large gap | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, ... | | Authors: | Xie, Y.F, Gao, G.F. | | Deposit date: | 2023-11-27 | | Release date: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Structural plasticity of human leptin binding to its receptor LepR
Hlife, 1, 2023
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