PDB: 533 resultsInfo pagesStatus searchChemie searchBIRD

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4RTW	Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 Descriptor: APP12 peptide, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 To be Published
4U5W	Crystal Structure of HIV-1 Nef-SF2 Core Domain in Complex with the Src Family Kinase Hck SH3-SH2 Tandem Regulatory Domains Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Protein Nef, ... Authors: Alvarado, J.J, Yeh, J.I, Smithgall, T.E. Deposit date: 2014-07-25 Release date: 2014-08-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment. J.Biol.Chem., 289, 2014
4QT7	Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein Descriptor: NS5A, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-07-07 Release date: 2014-12-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus. J.Struct.Biol., 189, 2015
2MOX	solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1 Descriptor: Sorbin and SH3 domain-containing protein 1 Authors: Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q. Deposit date: 2014-05-07 Release date: 2014-05-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
4ORZ	HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain Descriptor: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19 Authors: Geyer, M, Lulf, S. Deposit date: 2014-02-12 Release date: 2014-03-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody. Retrovirology, 11, 2014
4OMM	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2015-01-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4OMO	Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OML	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMN	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMQ	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant S94A Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2015-01-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4OMP	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4N78	The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton Descriptor: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ... Authors: Chen, Z.C. Deposit date: 2013-10-15 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.43 Å) Cite: The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton. Cell(Cambridge,Mass.), 156, 2014
4M4Z	SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2) Descriptor: Src-like-adapter 2 Authors: Wybenga-Groot, L.E, McGlade, C.J. Deposit date: 2013-08-07 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation. Cell Signal, 25, 2013
4LUD	Crystal Structure of HCK in complex with the fluorescent compound SKF86002 Descriptor: 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ... Authors: Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. Deposit date: 2013-07-25 Release date: 2014-02-12 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014
4LUE	Crystal Structure of HCK in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of SKF86002) Descriptor: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... Authors: Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. Deposit date: 2013-07-25 Release date: 2014-02-12 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014
4LN2	The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin Descriptor: Sorbin and SH3 domain-containing protein 1, proline rich peptide Authors: Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q. Deposit date: 2013-07-11 Release date: 2014-05-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1 Å) Cite: Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
4LE9	Crystal structure of a chimeric c-Src-SH3 domain Descriptor: Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M. Deposit date: 2013-06-25 Release date: 2014-05-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.344 Å) Cite: 3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops. J.Struct.Biol., 186, 2014
4K11	The structure of 1NA in complex with Src T338G Descriptor: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src Authors: Eck, M.J, Yun, C.H. Deposit date: 2013-04-04 Release date: 2014-04-09 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of 1NA in complex with Src T338G To be Published
4JZ4	Crystal structure of chicken c-Src-SH3 domain: monomeric form Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2013-04-02 Release date: 2014-04-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4JZ3	Crystal structure of the chicken c-Src-SH3 domain intertwined dimer Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A. Deposit date: 2013-04-02 Release date: 2014-04-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.852 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4JJC	Crystal structure of the Abl-SH3 domain at pH5 Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Abl-SH3 domain at pH5 To be Published
4JJB	Crystal structure of the Abl-SH3 domain at pH3 Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of the Abl-SH3 domain at pH3 To be Published
4JJD	Crystal structure of the N114A Abl-SH3 domain mutant at pH4 Descriptor: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Abl-SH3 domain at pH5 To be Published
4J9I	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 Descriptor: GLYCEROL, P17, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 To be Published
4J9F	Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 Descriptor: GLYCEROL, P0, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.094 Å) Cite: Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 To be Published

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