4OMO

Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E

Summary for 4OMO

Entry DOI	10.2210/pdb4omo/pdb
Related	3FJ5 4HVU 4HVV 4HVW 4JZ3 4JZ4
Descriptor	Proto-oncogene tyrosine-protein kinase Src, NICKEL (II) ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	beta-barrel sandwich, kinase, proline rich motifs, transferase
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Cell membrane : P00523
Total number of polymer chains	2
Total formula weight	14168.66
Authors	Camara-Artigas, A.,Bacarizo, J. (deposition date: 2014-01-27, release date: 2014-12-10, Last modification date: 2023-09-20)
Primary citation	Bacarizo, J.,Martinez-Rodriguez, S.,Martin-Garcia, J.M.,Andujar-Sanchez, M.,Ortiz-Salmeron, E.,Neira, J.L.,Camara-Artigas, A. Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9:e113224-e113224, 2014 Cited by PubMed: 25490095 DOI: 10.1371/journal.pone.0113224 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.04 Å)

Structure validation