Crystal structure of chicken c-Src-SH3 domain: monomeric form

Summary for 4JZ4

Related3FJ5 4JZ3
DescriptorProto-oncogene tyrosine-protein kinase Src, NICKEL (II) ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywordsbeta shandwich, sh3 domain, signaling pathways, signaling protein
Biological sourceGallus gallus (bantam,chickens)
Cellular locationCell membrane  P00523
Total number of polymer chains2
Total molecular weight14166.69
Camara-Artigas, A. (deposition date: 2013-04-02, release date: 2014-04-23, Last modification date: 2014-12-17)
Primary citation
Bacarizo, J.,Martinez-Rodriguez, S.,Martin-Garcia, J.M.,Andujar-Sanchez, M.,Ortiz-Salmeron, E.,Neira, J.L.,Camara-Artigas, A.
Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9:e113224-e113224, 2014
PubMed: 25490095 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0113224
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.17811.8%2.0%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4jz4
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