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PDB: 4 results

6XAR
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BU of 6xar by Molmil
Structure of CBL tyrosine kinase binding domain (TKBD) with C-terminal tail of Src-like kinase protein 2 (SLAP2)
Descriptor: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Src-like-adapter 2
Authors:Wybenga-Groot, L.E, McGlade, C.J.
Deposit date:2020-06-04
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.
J.Mol.Biol., 433, 2021
1H3H
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BU of 1h3h by Molmil
Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2
Authors:Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S.
Deposit date:2002-09-03
Release date:2003-03-06
Last modified:2013-07-24
Method:SOLUTION NMR
Cite:Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition
Mol.Cell, 11, 2003
2NMB
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BU of 2nmb by Molmil
DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.
Descriptor: PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN)
Authors:Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D.
Deposit date:1998-10-29
Release date:1998-11-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
Nat.Struct.Biol., 5, 1998
4M4Z
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SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
Descriptor: Src-like-adapter 2
Authors:Wybenga-Groot, L.E, McGlade, C.J.
Deposit date:2013-08-07
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013

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