7UH9
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![BU of 7uh9 by Molmil](/molmil-images/mine/7uh9) | NMR structure of the cNTnC-cTnI chimera bound to W8 | Descriptor: | CALCIUM ION, N-(7-aminoheptyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ... | Authors: | Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D. | Deposit date: | 2022-03-26 | Release date: | 2022-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7. Acs Chem.Biol., 17, 2022
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7V1A
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![BU of 7v1a by Molmil](/molmil-images/mine/7v1a) | Stapled TBS peptide from RIAM bound to talin R7R8 domains | Descriptor: | 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1 | Authors: | Zhang, P, Gao, T, Wu, J. | Deposit date: | 2022-05-11 | Release date: | 2023-06-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.845 Å) | Cite: | Inhibition of talin-induced integrin activation by a double-hit stapled peptide. Structure, 31, 2023
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7UHA
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![BU of 7uha by Molmil](/molmil-images/mine/7uha) | NMR structure of the cNTnC-cTnI chimera bound to W6 | Descriptor: | CALCIUM ION, N-(5-aminopentyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ... | Authors: | Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D. | Deposit date: | 2022-03-26 | Release date: | 2022-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7. Acs Chem.Biol., 17, 2022
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4UEB
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4ZRI
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![BU of 4zri by Molmil](/molmil-images/mine/4zri) | Crystal structure of Merlin-FERM and Lats2 | Descriptor: | Merlin, Serine/threonine-protein kinase LATS2 | Authors: | Li, F, Zhou, H, Long, J, Shen, Y. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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1QDS
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![BU of 1qds by Molmil](/molmil-images/mine/1qds) | SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM) | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Lambeir, A.M, Backmann, J, Ruiz-Sanz, J, Filimonov, V, Nielsen, J.E, Vriend, G, Kursula, I, Norledge, B.V, Wierenga, R.K. | Deposit date: | 1999-07-10 | Release date: | 2000-12-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase. Eur.J.Biochem., 267, 2000
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5OQT
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![BU of 5oqt by Molmil](/molmil-images/mine/5oqt) | |
7UKL
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4U66
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4K2R
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![BU of 4k2r by Molmil](/molmil-images/mine/4k2r) | Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yan, Q, Barros, T, Visperas, P.R, Deindl, S, Kadlecek, T.A, Weiss, A, Kuriyan, J. | Deposit date: | 2013-04-09 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker. Mol.Cell.Biol., 33, 2013
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1HXD
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![BU of 1hxd by Molmil](/molmil-images/mine/1hxd) | CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN | Descriptor: | BIOTIN, BIRA BIFUNCTIONAL PROTEIN | Authors: | Kwon, K, Streaker, E.D, Ruparelia, S, Beckett, D. | Deposit date: | 2001-01-12 | Release date: | 2001-05-30 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator. Proc.Natl.Acad.Sci.USA, 98, 2001
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4ZHY
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![BU of 4zhy by Molmil](/molmil-images/mine/4zhy) | Crystal structure of a bacterial signalling complex | Descriptor: | FORMIC ACID, SULFATE ION, YfiB, ... | Authors: | Li, S, Li, T, Wang, Y, Bartlam, M. | Deposit date: | 2015-04-27 | Release date: | 2016-04-27 | Method: | X-RAY DIFFRACTION (1.969 Å) | Cite: | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1 Sci Rep, 5, 2015
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7VG9
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![BU of 7vg9 by Molmil](/molmil-images/mine/7vg9) | |
2KNE
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![BU of 2kne by Molmil](/molmil-images/mine/2kne) | Calmodulin wraps around its binding domain in the plasma membrane CA2+ pump anchored by a novel 18-1 motif | Descriptor: | ATPase, Ca++ transporting, plasma membrane 4, ... | Authors: | Juranic, N, Atanasova, E, Filoteo, A.G, Macura, S, Prendergast, F.G, Penniston, J.T, Strehler, E.E. | Deposit date: | 2009-08-21 | Release date: | 2009-11-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Calmodulin wraps around its binding domain in the plasma membrane Ca2+ pump anchored by a novel 18-1 motif. J.Biol.Chem., 285, 2010
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4UNE
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![BU of 4une by Molmil](/molmil-images/mine/4une) | Human insulin B26Phe mutant crystal structure | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION | Authors: | Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. | Deposit date: | 2014-05-28 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
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2CVH
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![BU of 2cvh by Molmil](/molmil-images/mine/2cvh) | Crystal structure of the RadB recombinase | Descriptor: | DNA repair and recombination protein radB | Authors: | Akiba, T, Ishii, N, Rashid, N, Morikawa, M, Imanaka, T, Harata, K. | Deposit date: | 2005-06-03 | Release date: | 2005-08-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of RadB recombinase from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1: an implication for the formation of a near-7-fold helical assembly Nucleic Acids Res., 33, 2005
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7Y8W
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![BU of 7y8w by Molmil](/molmil-images/mine/7y8w) | Crystal structure of DLC-1/SAO-1 complex | Descriptor: | Dynein light chain 1, cytoplasmic, GLYCEROL, ... | Authors: | Yan, H, Zhao, C, Wei, Z, Yu, C. | Deposit date: | 2022-06-24 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Interaction between DLC-1 and SAO-1 facilitates CED-4 translocation during apoptosis in the Caenorhabditis elegans germline. Cell Death Discov, 8, 2022
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2CVF
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![BU of 2cvf by Molmil](/molmil-images/mine/2cvf) | Crystal structure of the RadB recombinase | Descriptor: | DNA repair and recombination protein radB | Authors: | Akiba, T, Ishii, N, Rashid, N, Morikawa, M, Imanaka, T, Harata, K. | Deposit date: | 2005-06-03 | Release date: | 2005-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of RadB recombinase from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1: an implication for the formation of a near-7-fold helical assembly Nucleic Acids Res., 33, 2005
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3T6Q
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![BU of 3t6q by Molmil](/molmil-images/mine/3t6q) | Crystal structure of mouse RP105/MD-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD180 antigen, ... | Authors: | Ohto, U, Shimizu, T. | Deposit date: | 2011-07-28 | Release date: | 2011-11-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family. J.Mol.Biol., 413, 2011
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3NMO
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4ZKT
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4ZRJ
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![BU of 4zrj by Molmil](/molmil-images/mine/4zrj) | Structure of Merlin-FERM and CTD | Descriptor: | GLYCEROL, Merlin | Authors: | Lin, Z, Li, F, Long, J, Shen, Y. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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2F60
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![BU of 2f60 by Molmil](/molmil-images/mine/2f60) | Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein | Descriptor: | GLYCEROL, Pyruvate dehydrogenase protein X component | Authors: | Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T. | Deposit date: | 2005-11-28 | Release date: | 2006-01-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex. Structure, 14, 2006
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4Z9S
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4ZM9
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![BU of 4zm9 by Molmil](/molmil-images/mine/4zm9) | Crystal structure of circularly permuted human asparaginase-like protein 1 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CITRATE ANION, ... | Authors: | Li, W.Z, Zhang, Y. | Deposit date: | 2015-05-02 | Release date: | 2016-02-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages. Biochemistry, 55, 2016
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