7V1A

Stapled TBS peptide from RIAM bound to talin R7R8 domains

Summary for 7V1A

• Entry DOI: 10.2210/pdb7v1a/pdb
• Descriptor: Talin-1, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: riam, talin, integrin, mrl, stapled, helix, cell adhesion
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 33845.17

Authors

Zhang, P.,Gao, T.,Wu, J. (deposition date: 2022-05-11, release date: 2023-06-14, Last modification date: 2023-11-15)

• Primary citation: Gao, T.,Cho, E.A.,Zhang, P.,Wu, J.; Inhibition of talin-induced integrin activation by a double-hit stapled peptide.; Structure, 31:948-, 2023; PubMed: 37369205; DOI: 10.1016/j.str.2023.05.016

Experimental method

X-RAY DIFFRACTION (1.845 Å)