6VC6
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![BU of 6vc6 by Molmil](/molmil-images/mine/6vc6) | 2.1 Angstrom Resolution Crystal Structure of 6-phospho-alpha-glucosidase from Gut Microorganisms in Complex with NAD and Mn2+ | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, 6-phospho-alpha-glucosidase, GLYCEROL, ... | Authors: | Wu, R, Kim, Y, Endres, M, Joachimiak, J. | Deposit date: | 2019-12-20 | Release date: | 2020-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.133 Å) | Cite: | 2.1 Angstrom Resolution Crystal Structure of 6-phospho-alpha-glucosidase from Gut Microorganisms in Complex with NAD and Mn2+ To Be Published
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4KTX
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![BU of 4ktx by Molmil](/molmil-images/mine/4ktx) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 167-174 stretch | Descriptor: | Botulinum neurotoxin A light chain, GLYCEROL, Peptide inhibitor MPT-DPP-ARG-G-LEU-NH2, ... | Authors: | Stura, E.A, Vera, L, Guitot, K, Dive, V. | Deposit date: | 2013-05-21 | Release date: | 2014-10-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Covalent modification of the active site cysteine stresses Clostridium botulinum neurotoxin A To be Published
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8GS5
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![BU of 8gs5 by Molmil](/molmil-images/mine/8gs5) | Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form | Descriptor: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-04 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.486 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRD
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![BU of 8grd by Molmil](/molmil-images/mine/8grd) | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | Authors: | Chen, X, Sun, P, Ding, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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6VC9
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![BU of 6vc9 by Molmil](/molmil-images/mine/6vc9) | TB19 complex | Descriptor: | 1,2-ETHANEDIOL, 5'-nucleotidase, ecto (CD73), ... | Authors: | Zhou, Y.F, Lord, D.M. | Deposit date: | 2019-12-20 | Release date: | 2020-11-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms. J.Biol.Chem., 295, 2020
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6VDH
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![BU of 6vdh by Molmil](/molmil-images/mine/6vdh) | |
8GRG
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![BU of 8grg by Molmil](/molmil-images/mine/8grg) | |
6VCK
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![BU of 6vck by Molmil](/molmil-images/mine/6vck) | Crystal structure of E.coli RppH-DapF in complex with GDP, Mg2+ and F- | Descriptor: | CHLORIDE ION, Diaminopimelate epimerase, FLUORIDE ION, ... | Authors: | Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A. | Deposit date: | 2019-12-21 | Release date: | 2020-02-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res., 48, 2020
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8GRH
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![BU of 8grh by Molmil](/molmil-images/mine/8grh) | Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT | Descriptor: | CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.506 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRU
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![BU of 8gru by Molmil](/molmil-images/mine/8gru) | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | Descriptor: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-02 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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6VCP
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![BU of 6vcp by Molmil](/molmil-images/mine/6vcp) | Crystal structure of E.coli RppH in complex with UTP | Descriptor: | RNA pyrophosphohydrolase, URIDINE 5'-TRIPHOSPHATE | Authors: | Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A. | Deposit date: | 2019-12-21 | Release date: | 2020-02-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res., 48, 2020
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1F2F
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![BU of 1f2f by Molmil](/molmil-images/mine/1f2f) | SRC SH2 THREF1TRP MUTANT | Descriptor: | PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | Authors: | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | Deposit date: | 2000-05-24 | Release date: | 2000-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for specificity switching of the Src SH2 domain. Mol.Cell, 5, 2000
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5B48
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![BU of 5b48 by Molmil](/molmil-images/mine/5b48) | 2-Oxoacid:Ferredoxin Oxidoreductase 1 from Sulfolobus tokodai | Descriptor: | 2-[(2E)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-(1-oxidanylpropylidene)-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-oxoacid--ferredoxin oxidoreductase alpha subunit, 2-oxoacid--ferredoxin oxidoreductase beta subunit, ... | Authors: | Yan, Z, Maruyama, A, Arakawa, T, Fushinobu, S, Wakagi, T. | Deposit date: | 2016-04-01 | Release date: | 2016-09-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of archaeal 2-oxoacid:ferredoxin oxidoreductases from Sulfolobus tokodaii Sci Rep, 6, 2016
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8GRB
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![BU of 8grb by Molmil](/molmil-images/mine/8grb) | |
6BAK
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![BU of 6bak by Molmil](/molmil-images/mine/6bak) | The structure of the Stigmatella aurantiaca phytochrome chromophore binding domain T289H mutant | Descriptor: | 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Photoreceptor-histidine kinase BphP | Authors: | Schmidt, M, Stojkovic, E. | Deposit date: | 2017-10-13 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome. IUCrJ, 5, 2018
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1F35
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8GMU
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![BU of 8gmu by Molmil](/molmil-images/mine/8gmu) | Structure of lambda repressor in complex with RecA filament | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gao, B, Feng, Y. | Deposit date: | 2022-08-22 | Release date: | 2022-12-21 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis for regulation of SOS response in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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4EJI
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![BU of 4eji by Molmil](/molmil-images/mine/4eji) | |
8GMT
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![BU of 8gmt by Molmil](/molmil-images/mine/8gmt) | Structure of UmuD in complex with RecA filament | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), DNA polymerase V subunit UmuD, MAGNESIUM ION, ... | Authors: | Gao, B, Feng, Y. | Deposit date: | 2022-08-22 | Release date: | 2022-12-21 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Structural basis for regulation of SOS response in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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6UXZ
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![BU of 6uxz by Molmil](/molmil-images/mine/6uxz) | (S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR | Descriptor: | (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid, HTH-type transcriptional regulatory protein GabR, SULFATE ION | Authors: | Catlin, D.S, Liu, D. | Deposit date: | 2019-11-09 | Release date: | 2020-10-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR. Protein Sci., 29, 2020
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8GTL
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![BU of 8gtl by Molmil](/molmil-images/mine/8gtl) | Crystal Structure of Cytochrome P450 (CYP101D5) | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 CYP101D5 | Authors: | Do, H, Lee, J.H. | Deposit date: | 2022-09-08 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure and Biochemical Analysis of a Cytochrome P450 CYP101D5 from Sphingomonas echinoides. Int J Mol Sci, 23, 2022
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4LB2
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![BU of 4lb2 by Molmil](/molmil-images/mine/4lb2) | X-ray study of human serum albumin complexed with idarubicin | Descriptor: | IDARUBICIN, SERUM ALBUMIN | Authors: | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | Deposit date: | 2013-06-20 | Release date: | 2013-07-24 | Last modified: | 2014-02-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830, 2013
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5B6C
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![BU of 5b6c by Molmil](/molmil-images/mine/5b6c) | Structural Details of Ufd1 binding to p97 | Descriptor: | Peptide from Ubiquitin fusion degradation protein 1 homolog, Transitional endoplasmic reticulum ATPase | Authors: | Le, L.T.M, Yang, J.K. | Deposit date: | 2016-05-26 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation PLoS ONE, 11, 2016
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1F6O
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![BU of 1f6o by Molmil](/molmil-images/mine/1f6o) | CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(YRR)P*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-06-22 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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8GZ3
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![BU of 8gz3 by Molmil](/molmil-images/mine/8gz3) | |