6UXZ
(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR
Summary for 6UXZ
Entry DOI | 10.2210/pdb6uxz/pdb |
Descriptor | HTH-type transcriptional regulatory protein GabR, SULFATE ION, (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid (3 entities in total) |
Functional Keywords | gabr transcription factor, selective agonist gaba. metabolism, transcription |
Biological source | Bacillus subtilis (strain 168) |
Total number of polymer chains | 2 |
Total formula weight | 85269.11 |
Authors | Catlin, D.S.,Liu, D. (deposition date: 2019-11-09, release date: 2020-10-07, Last modification date: 2024-04-03) |
Primary citation | Catlin, D.S.,Reidl, C.T.,Trzupek, T.R.,Silverman, R.B.,Cannon, B.L.,Becker, D.P.,Liu, D. (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR. Protein Sci., 29:1816-1828, 2020 Cited by PubMed: 32557944DOI: 10.1002/pro.3905 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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