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5YEF	Crystal structure of CTCF ZFs2-8-Hs5-1aE Descriptor: DNA (27-MER), Transcriptional repressor CTCF, ZINC ION Authors: Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. Deposit date: 2017-09-17 Release date: 2017-11-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.807 Å) Cite: Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5WJ7	Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4 Descriptor: DNA repair protein XRCC4,Myosin-7 Authors: Andreas, M.P, Ajay, G, Gellings, J, Rayment, I. Deposit date: 2017-07-21 Release date: 2017-08-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod. J. Struct. Biol., 200, 2017
4CI3	Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide Descriptor: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Pomalidomide, ... Authors: Fischer, E.S, Boehm, K, Thoma, N.H. Deposit date: 2013-12-05 Release date: 2014-07-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Nature, 512, 2014
4CI1	Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide Descriptor: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ... Authors: Fischer, E.S, Boehm, K, Thoma, N.H. Deposit date: 2013-12-05 Release date: 2014-07-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Nature, 512, 2014
4PZ6	PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD Descriptor: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.406 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
3LJ5	Full Length Bacteriophage P22 Portal Protein Descriptor: Portal protein Authors: Olia, A.S, Cingolani, G. Deposit date: 2010-01-25 Release date: 2011-04-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (7.497 Å) Cite: Three-dimensional structure of a viral genome-delivery portal vertex. Nat.Struct.Mol.Biol., 18, 2011
5CY2	Tn3 resolvase - site III complex crystal form II Descriptor: DNA (27-MER), Transposon Tn3 resolvase Authors: Montano, P.S, Rice, P.A. Deposit date: 2015-07-30 Release date: 2017-01-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (4 Å) Cite: Structures of resolvase - accessory site complexes To Be Published
4CI2	Structure of the DDB1-CRBN E3 ubiquitin ligase bound to lenalidomide Descriptor: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Lenalidomide, ... Authors: Fischer, E.S, Boehm, K, Thoma, N.H. Deposit date: 2013-12-05 Release date: 2014-07-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Nature, 512, 2014
6H0F	Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) Descriptor: DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, DNA-binding protein Ikaros, Protein cereblon, ... Authors: Petzold, G, Bunker, R.D, Thoma, N.H. Deposit date: 2018-07-09 Release date: 2018-11-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science, 362, 2018
315D	CRYSTAL STRUCTURE OF AN ALTERNATING OCTAMER R(GUAUGUA)D(C) WITH ADJACENT G-U WOBBLE PAIRS Descriptor: DNA/RNA (5'-R(*GP*UP*AP*UP*GP*UP*AP*)-D(*C)-3') Authors: Biswas, R, Wahl, M.C, Ban, C, Sundaralingam, M. Deposit date: 1997-02-26 Release date: 1997-09-23 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Crystal structure of an alternating octamer r(GUAUGUA)dC with adjacent G x U wobble pairs J.Mol.Biol., 267, 1997
2N4Y	Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome Descriptor: DNA_(5'-D(*CP*TP*GP*GP*GP*CP*GP*GP*GP*AP*CP*TP*GP*GP*GP*GP*AP*GP*TP*GP*GP*T)-3') Authors: DeNicola, B, Lech, C.J, Heddi, B, Regmi, S, Frasson, I, Perrone, R, Richter, S.N, Phan, A.T. Deposit date: 2015-07-02 Release date: 2016-06-29 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome. Nucleic Acids Res., 44, 2016
7B3B	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) Descriptor: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... Authors: Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. Deposit date: 2020-11-30 Release date: 2020-12-23 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
7B3C	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -4 (structure 2) Descriptor: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*A)-D(P*(RMP))-R(P*GP*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... Authors: Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. Deposit date: 2020-11-30 Release date: 2020-12-23 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
5UH7	Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase Descriptor: DNA-directed RNA polymerase subunit beta' Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2017-01-11 Release date: 2017-04-12 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.199 Å) Cite: Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
6R75	Crystal structure of human Ube2T E54R mutant Descriptor: Ubiquitin-conjugating enzyme E2 T Authors: Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R. Deposit date: 2019-03-28 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Allosteric mechanism for site-specific ubiquitination of FANCD2. Nat.Chem.Biol., 16, 2020
7KBV	Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking sequence Descriptor: Myc2345 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
7KBW	Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking in complex with NSC85697, a quinoline derivative Descriptor: 2-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-1-methyl-quinoline-4-carboxamide, Myc2345 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
7KBX	Solution structure of the major MYC promoter G-quadruplex in complex with NSC85697, a quinoline derivative Descriptor: 2-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-1-methyl-quinoline-4-carboxamide, Myc2345_T23 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
3WAA	The nucleosome containing human H2A.Z.2 Descriptor: DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ... Authors: Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. Deposit date: 2013-04-30 Release date: 2013-12-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
7XUR	The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE Descriptor: DNA (35-MER), ZINC ION, snRNA-activating protein complex subunit 1, ... Authors: Wang, W, Sun, J.F. Deposit date: 2022-05-19 Release date: 2022-12-07 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter. Nat Commun, 13, 2022
2LTO	TDRD3 complex Descriptor: DNA-directed RNA polymerase II subunit RPB1, Tudor domain-containing protein 3 Authors: Sikorsky, T. Deposit date: 2012-05-30 Release date: 2013-01-16 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Recognition of asymmetrically dimethylated arginine by TDRD3. Nucleic Acids Res., 40, 2012
6MC8	Crystal structure of PprA dimer from Deinococcus deserti Descriptor: DNA repair protein PprA Authors: Szabla, R, Junop, M.S, Rok, M. Deposit date: 2018-08-30 Release date: 2018-09-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of PprA from Deinococcus radiodurans To Be Published
377D	5'-R(*CP*GP*UP*AP*CP*DG)-3' Descriptor: RNA-DNA (5'-R(*CP*GP*UP*AP*CP*DG)-3') Authors: Biswas, R, Mitra, S.N, Sundaralingam, M. Deposit date: 1998-01-26 Release date: 1998-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.76 Å) Cite: 1.76 A structure of a pyrimidine start alternating A-RNA hexamer r(CGUAC)dG. Acta Crystallogr.,Sect.D, 54, 1998
4JBK	Molecular basis for abrogation of activation of pro-inflammatory cytokines Descriptor: DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3'), Interferon-activable protein 202 Authors: Ru, H, Ni, X, Crowley, C, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J. Deposit date: 2013-02-19 Release date: 2013-06-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.963 Å) Cite: Structural basis for termination of AIM2-mediated signaling by p202 Cell Res., 23, 2013
1Y14	Crystal structure of yeast subcomplex of Rpb4 and Rpb7 Descriptor: DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II 32 kDa polypeptide Authors: Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. Deposit date: 2004-11-17 Release date: 2004-12-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7 J.Biol.Chem., 280, 2005

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