6O8Q
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![BU of 6o8q by Molmil](/molmil-images/mine/6o8q) | HUaa 19bp SYM DNA pH 4.5 | Descriptor: | DNA (57-MER), DNA-binding protein HU-alpha | Authors: | Remesh, S.G, Hammel, M. | Deposit date: | 2019-03-11 | Release date: | 2020-03-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.216 Å) | Cite: | Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling. Nat Commun, 11, 2020
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6OCA
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![BU of 6oca by Molmil](/molmil-images/mine/6oca) | Ricin A chain bound to VHH antibody V2G10 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ... | Authors: | Rudolph, M.J. | Deposit date: | 2019-03-22 | Release date: | 2020-04-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.113 Å) | Cite: | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
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8GNG
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![BU of 8gng by Molmil](/molmil-images/mine/8gng) | Crystal structure of human adenosine A2A receptor in complex with istradefylline. | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione, Adenosine receptor A2a, ... | Authors: | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | Deposit date: | 2022-08-23 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist. Mol.Pharmacol., 103, 2023
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1SC6
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![BU of 1sc6 by Molmil](/molmil-images/mine/1sc6) | |
6QCY
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![BU of 6qcy by Molmil](/molmil-images/mine/6qcy) | MloK1 model from single particle analysis of 2D crystals, class 2 (intermediate conformation) | Descriptor: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | Authors: | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | Deposit date: | 2018-12-31 | Release date: | 2019-04-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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8GUW
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![BU of 8guw by Molmil](/molmil-images/mine/8guw) | |
6Q7P
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![BU of 6q7p by Molmil](/molmil-images/mine/6q7p) | Crystal structure of OE1.2 | Descriptor: | 1,2-ETHANEDIOL, 1-PHENYLETHANONE, MAGNESIUM ION, ... | Authors: | Levy, C.W. | Deposit date: | 2018-12-13 | Release date: | 2019-06-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Design and evolution of an enzyme with a non-canonical organocatalytic mechanism. Nature, 570, 2019
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2WES
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![BU of 2wes by Molmil](/molmil-images/mine/2wes) | |
8GNE
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![BU of 8gne by Molmil](/molmil-images/mine/8gne) | Crystal structure of human adenosine A2A receptor in complex with an insurmountable inverse agonist, KW-6356. | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Adenosine receptor A2a,Soluble cytochrome b562, ... | Authors: | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | Deposit date: | 2022-08-23 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist. Mol.Pharmacol., 103, 2023
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6OON
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![BU of 6oon by Molmil](/molmil-images/mine/6oon) | Human Argonaute4 bound to guide RNA | Descriptor: | Protein argonaute-4, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3') | Authors: | Park, M.S, Brackbill, J.A, Nakanishi, K. | Deposit date: | 2019-04-23 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters. Mol.Cell, 75, 2019
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2W6V
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![BU of 2w6v by Molmil](/molmil-images/mine/2w6v) | Structure of Human deoxy Hemoglobin A in complex with Xenon | Descriptor: | GLYCEROL, HEMOGLOBIN SUBUNIT ALPHA, HEMOGLOBIN SUBUNIT BETA, ... | Authors: | Miele, A.E, Draghi, F, Sciara, G, Johnson, K.A, Renzi, F, Vallone, B, Brunori, M, Savino, C. | Deposit date: | 2008-12-19 | Release date: | 2009-04-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Pattern of Cavities in Globins: The Case of Human Hemoglobin. Biopolymers, 91, 2009
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2WFL
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![BU of 2wfl by Molmil](/molmil-images/mine/2wfl) | Crystal structure of polyneuridine aldehyde esterase | Descriptor: | POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION | Authors: | Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J. | Deposit date: | 2009-04-08 | Release date: | 2009-08-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids. Angew.Chem.Int.Ed.Engl., 48, 2009
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8GAR
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![BU of 8gar by Molmil](/molmil-images/mine/8gar) | |
8GKH
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![BU of 8gkh by Molmil](/molmil-images/mine/8gkh) | Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA | Descriptor: | DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2023-03-19 | Release date: | 2023-07-05 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Fanzor is a eukaryotic programmable RNA-guided endonuclease. Nature, 620, 2023
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6Q7R
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![BU of 6q7r by Molmil](/molmil-images/mine/6q7r) | |
6Q9P
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![BU of 6q9p by Molmil](/molmil-images/mine/6q9p) | Crystal structure of human Arginase-1 at pH 9.0 in complex with ABH | Descriptor: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ... | Authors: | Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R. | Deposit date: | 2018-12-18 | Release date: | 2019-12-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X, 4, 2020
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6QD2
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![BU of 6qd2 by Molmil](/molmil-images/mine/6qd2) | MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation) | Descriptor: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | Authors: | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | Deposit date: | 2018-12-31 | Release date: | 2019-04-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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8GA8
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![BU of 8ga8 by Molmil](/molmil-images/mine/8ga8) | Structure of the yeast (HDAC) Rpd3L complex | Descriptor: | Histone deacetylase RPD3, Transcriptional regulatory protein DEP1, Transcriptional regulatory protein PHO23, ... | Authors: | Patel, A.B, Radhakrishnan, I, He, Y. | Deposit date: | 2023-02-22 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. Nat Commun, 14, 2023
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2X5Z
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![BU of 2x5z by Molmil](/molmil-images/mine/2x5z) | Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GDP-mannose. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE | Authors: | Pelissier, M.C, Lesley, S, Kuhn, P, Bourne, Y. | Deposit date: | 2010-02-12 | Release date: | 2010-06-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insights Into the Catalytic Mechanism of Bacterial Guanosine-Diphospho-D-Mannose Pyrophosphorylase and its Regulation by Divalent Ions. J.Biol.Chem., 285, 2010
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6Q7M
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![BU of 6q7m by Molmil](/molmil-images/mine/6q7m) | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | Authors: | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | Deposit date: | 2018-12-13 | Release date: | 2020-02-12 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex. Commun Biol, 3, 2020
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2WSI
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![BU of 2wsi by Molmil](/molmil-images/mine/2wsi) | |
6OBC
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![BU of 6obc by Molmil](/molmil-images/mine/6obc) | Ricin A chain bound to camelid | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ... | Authors: | Rudolph, M.J. | Deposit date: | 2019-03-20 | Release date: | 2020-04-01 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (1.762 Å) | Cite: | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
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8GJ9
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2V50
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![BU of 2v50 by Molmil](/molmil-images/mine/2v50) | |
8GJA
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![BU of 8gja by Molmil](/molmil-images/mine/8gja) | RAD51C-XRCC3 structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, RAD51C, ... | Authors: | Arvai, A.S, Tainer, J.A, Williams, G, Longo, M.A. | Deposit date: | 2023-03-15 | Release date: | 2023-08-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. Nat Commun, 14, 2023
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