6OON

Human Argonaute4 bound to guide RNA

Summary for 6OON

• Entry DOI: 10.2210/pdb6oon/pdb
• Descriptor: Protein argonaute-4, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3') (3 entities in total)
• Functional Keywords: rna, mirna, rna binding protein, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 101233.42

Authors

Park, M.S.,Brackbill, J.A.,Nakanishi, K. (deposition date: 2019-04-23, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Park, M.S.,Araya-Secchi, R.,Brackbill, J.A.,Phan, H.D.,Kehling, A.C.,Abd El-Wahab, E.W.,Dayeh, D.M.,Sotomayor, M.,Nakanishi, K.; Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters.; Mol.Cell, 75:725-740.e6, 2019; PubMed: 31324450; DOI: 10.1016/j.molcel.2019.06.011

Experimental method

X-RAY DIFFRACTION (1.9 Å)