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7XNP
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BU of 7xnp by Molmil
Structure of nucleosome-AAG complex (A-55I, post-catalytic state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-29
Release date:2023-05-03
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
5DNM
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BU of 5dnm by Molmil
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Muhammad, R, Davey, C.A.
Deposit date:2015-09-10
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
2KWO
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BU of 2kwo by Molmil
Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-14
Release date:2010-07-14
Last modified:2025-03-26
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2KWN
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BU of 2kwn by Molmil
Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-13
Release date:2010-07-14
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
5E5A
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BU of 5e5a by Molmil
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
Descriptor: C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ...
Authors:Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
7XFJ
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BU of 7xfj by Molmil
Structure of nucleosome-AAG complex (T-50I, post-catalytic state)
Descriptor: DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-11-08
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
5OXV
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BU of 5oxv by Molmil
Structure of the 4_601_157 tetranucleosome (C2 form)
Descriptor: DNA STRAND 1 (601-based sequence model), DNA STRAND 2 (601-based sequence model), Histone H2A, ...
Authors:Ekundayo, B, Schalch, T.
Deposit date:2017-09-07
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (6.721 Å)
Cite:Capturing Structural Heterogeneity in Chromatin Fibers.
J. Mol. Biol., 429, 2017
7ZSA
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BU of 7zsa by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7ZSB
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BU of 7zsb by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7ZS9
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BU of 7zs9 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
5OY7
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BU of 5oy7 by Molmil
Structure of the 4_601_157 tetranucleosome (P1 form)
Descriptor: CHLORIDE ION, DNA (619-MER), Histone H2A, ...
Authors:Ekundayo, B, Richmond, T.J, Schalch, T.
Deposit date:2017-09-07
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (5.774 Å)
Cite:Capturing Structural Heterogeneity in Chromatin Fibers.
J. Mol. Biol., 429, 2017
7XFL
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BU of 7xfl by Molmil
Structure of nucleosome-AAG complex (A-53I, free state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
5DNN
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BU of 5dnn by Molmil
Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Ma, Z, Davey, C.A.
Deposit date:2015-09-10
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
5F99
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BU of 5f99 by Molmil
X-ray Structure of the MMTV-A Nucleosome Core Particle
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A type 1, ...
Authors:Frouws, T.D, Richmond, T.J.
Deposit date:2015-12-09
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:X-ray structure of the MMTV-A nucleosome core.
Proc.Natl.Acad.Sci.USA, 113, 2016
8AAG
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BU of 8aag by Molmil
H1-bound palindromic nucleosome, state 1
Descriptor: DNA/RNA (185-MER), Histone H1.0-B, Histone H2A type 1, ...
Authors:Alegrio Louro, J, Beinsteiner, B, Cheng, T.C, Patel, A.K.M, Boopathi, R, Angelov, D, Hamiche, A, Bednar, J, Kale, S, Dimitrov, S, Klaholz, B.
Deposit date:2022-07-01
Release date:2022-12-14
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms.
Structure, 31, 2023
5NL0
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BU of 5nl0 by Molmil
Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1
Descriptor: DNA (197-MER), Histone H1.0-B, Histone H2A type 1, ...
Authors:Garcia-Saez, I, Petosa, C, Dimitrov, S.
Deposit date:2017-04-03
Release date:2017-05-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (5.4 Å)
Cite:Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.
Mol. Cell, 66, 2017
5O9G
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BU of 5o9g by Molmil
Structure of nucleosome-Chd1 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
Authors:Farnung, L, Vos, S.M, Wigge, C, Cramer, P.
Deposit date:2017-06-19
Release date:2017-10-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Nucleosome-Chd1 structure and implications for chromatin remodelling.
Nature, 550, 2017
6KW3
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BU of 6kw3 by Molmil
The ClassA RSC-Nucleosome Complex
Descriptor: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
Authors:Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
Deposit date:2019-09-05
Release date:2019-11-13
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.13 Å)
Cite:Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
2KYU
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BU of 2kyu by Molmil
The solution structure of the PHD3 finger of MLL
Descriptor: Histone-lysine N-methyltransferase MLL, ZINC ION
Authors:Park, S, Bushweller, J.H.
Deposit date:2010-06-08
Release date:2010-08-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression.
Biochemistry, 49, 2010
8UNI
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BU of 8uni by Molmil
LSD1-CoREST with N-formyl-FAD in complex with H3K4M histone tail
Descriptor: Histone H3 (Fragment), Lysine-specific histone demethylase 1A, REST corepressor 1, ...
Authors:Caroli, J, Mattevi, A.
Deposit date:2023-10-19
Release date:2025-02-05
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To Be Published
8UOM
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BU of 8uom by Molmil
LSD1-CoREST with N-formyl-FAD in complex with H3dimeK4 histone tail
Descriptor: Histone H3 (Fragment), Lysine-specific histone demethylase 1A, REST corepressor 1, ...
Authors:Caroli, J, Mattevi, A.
Deposit date:2023-10-20
Release date:2025-02-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To Be Published
8UT7
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BU of 8ut7 by Molmil
CryoEM structure of A/Perth/16/2009 H3 in complex with polyclonal Fab from mice immunized with H3 stem nanoparticles-28 days post immunization
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H3D28 pFab HC Fv_polyA, ...
Authors:Huang, J, Han, J, Ward, A.B.
Deposit date:2023-10-30
Release date:2024-05-08
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
4XUJ
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BU of 4xuj by Molmil
Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2015-01-26
Release date:2016-01-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands
To Be Published
4WU9
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BU of 4wu9 by Molmil
Structure of cisPtNAP-NCP145
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Chua, E.Y.D, Davey, G.E, Chin, C.F, Droge, P, Ang, W.H, Davey, C.A.
Deposit date:2014-10-31
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
3B7B
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BU of 3b7b by Molmil
EuHMT1 (Glp) Ankyrin Repeat Domain (Structure 1)
Descriptor: Euchromatic histone-lysine N-methyltransferase 1, SULFATE ION
Authors:Collins, R.E, Horton, J.R, Cheng, X.
Deposit date:2007-10-30
Release date:2008-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules
Nat.Struct.Mol.Biol., 15, 2008

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數據於2025-07-09公開中

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