5E5A

Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle

Summary for 5E5A

• Entry DOI: 10.2210/pdb5e5a/pdb
• Descriptor: DNA (146-MER), Histone H3.2, Histone H4, ... (8 entities in total)
• Functional Keywords: ncp, ie1, hcmv, ctd, protein binding-viral protein-dna complex, protein binding/viral protein/dna
• Biological source: Homo sapiens (Humam); More
• Cellular location: Nucleus: P84233 P62799 P02281
• Total number of polymer chains: 11
• Total formula weight: 201100.70

Authors

Fang, Q.,Chen, P.,Wang, M.,Fang, J.,Yang, N.,Li, G.,Xu, R.M. (deposition date: 2015-10-08, release date: 2016-02-03, Last modification date: 2023-11-08)

• Primary citation: Fang, Q.,Chen, P.,Wang, M.,Fang, J.,Yang, N.,Li, G.,Xu, R.M.; Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome; Elife, 5:-, 2016; PubMed: 26812545; DOI: 10.7554/eLife.11911

Experimental method

X-RAY DIFFRACTION (2.809 Å)