5E5A

Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle

Summary for 5E5A

DescriptorDNA (146-MER), Histone H3.2, Histone H4, ... (8 entities in total)
Functional Keywordsncp, ie1, hcmv, ctd, protein binding-viral protein-dna complex, protein binding/viral protein/dna
Biological sourceHomo sapiens (Humam)
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Cellular locationNucleus P84233 P62799 P02281
Total number of polymer chains11
Total molecular weight201100.7
Authors
Fang, Q.,Chen, P.,Wang, M.,Fang, J.,Yang, N.,Li, G.,Xu, R.M. (deposition date: 2015-10-08, release date: 2016-02-03, Last modification date: 2017-10-18)
Primary citation
Fang, Q.,Chen, P.,Wang, M.,Fang, J.,Yang, N.,Li, G.,Xu, R.M.
Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5:-, 2016
PubMed: 26812545 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.11911
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.809 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23940.3%0.3%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5e5a
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Molmil generated image of 5e5a
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Molmil generated image of 5e5a
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