5E5A

Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, J	DNA (146-MER)	polymer	146	45054.8	2		Homo sapiens (Humam)
2	A, E	Histone H3.2	polymer	136	15435.1	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
3	B, F	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
4	C, G	Histone H2A	polymer	130	14109.4	2	UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB	Xenopus laevis (African clawed frog)
5	D, H	Histone H2B 1.1	polymer	123	13655.9	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)	H2B1.1
6	K	C-terminal domain of Regulatory protein IE1	polymer	16	1703.9	1	UniProt (Q6SWP6) UniProt (by SIFTS) (P03169) In PDB	Human herpesvirus 5 strain Towne
7	I, C, D, E	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
8		water	water		18.0	230	Chemie (HOH)

Sequence modifications

A, E: 0 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	conflict

D, H: 1 - 122 (UniProt: P02281)

PDB	External Database	Details
Met 0	-	expression tag
Thr 29	Ser 33	conflict

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	201003.5
Non-Polymers*	Number of molecules	4
	Total formula weight	97.2
All*	Total formula weight	201100.7

*Water molecules are not included.