5E5A
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (I, J) | DNA (146-MER) | polymer | 146 | 45054.8 | 2 | Homo sapiens (Humam) | ||
| 2 | C, G (A, E) | Histone H3.2 | polymer | 136 | 15435.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 3 | D, H (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 4 | E, I (C, G) | Histone H2A | polymer | 130 | 14109.4 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Xenopus laevis (African clawed frog) | |
| 5 | F, J (D, H) | Histone H2B 1.1 | polymer | 123 | 13655.9 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 6 | K (K) | C-terminal domain of Regulatory protein IE1 | polymer | 16 | 1703.9 | 1 | UniProt (Q6SWP6) UniProt (by SIFTS) (P03169) | Human herpesvirus 5 strain Towne | |
| 7 | L, M, N, O (I, C, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 8 | P, Q, R, S, T... (I, J, A, B, C...) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A, E: 0 - 135 (UniProt: P84233)
D, H: 1 - 122 (UniProt: P02281)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Thr 29 | Ser 33 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 201003.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 97.2 | |
| All* | Total formula weight | 201100.7 |
