PDB: 66507 resultsInfo pagesStatus searchChemie searchBIRD

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3VZQ	Crystal structure of Q47L mutant of PhaB from Ralstonia eutropha Descriptor: Acetoacetyl-CoA reductase Authors: Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. Deposit date: 2012-10-15 Release date: 2013-08-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics Appl.Environ.Microbiol., 79, 2013
4MB9	Structure of Streptococcus pneumonia ParE in complex with AZ13102335 Descriptor: 1-ethyl-3-{6-(pyrimidin-5-yl)-5-[(3R)-tetrahydrofuran-3-ylmethoxy][1,3]thiazolo[5,4-b]pyridin-2-yl}urea, DNA topoisomerase IV, B subunit, ... Authors: Ogg, D, Tucker, J. Deposit date: 2013-08-19 Release date: 2013-10-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
4MBC	Structure of Streptococcus pneumonia ParE in complex with AZ13053807 Descriptor: 1-{5-[2-(morpholin-4-yl)ethoxy]-6-(pyridin-3-yl)[1,3]thiazolo[5,4-b]pyridin-2-yl}-3-prop-2-en-1-ylurea, DNA topoisomerase IV, B subunit Authors: Ogg, D, Tucker, J. Deposit date: 2013-08-19 Release date: 2013-10-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
6S9A	Artificial GTPase-BSE dimer of human Dynamin1 Descriptor: CHLORIDE ION, Dynamin-1,Dynamin-1, ZINC ION Authors: Ganichkin, O.M, Vancraenenbroeck, R, Rosenblum, G, Hofmann, H, Daumke, O, Noel, J.K. Deposit date: 2019-07-11 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor. Proc.Natl.Acad.Sci.USA, 118, 2021
3IMX	Crystal Structure of human glucokinase in complex with a synthetic activator Descriptor: (2R)-3-cyclopentyl-N-(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}propanamide, Glucokinase, SODIUM ION, ... Authors: Stams, T, Vash, B. Deposit date: 2009-08-11 Release date: 2009-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. J.Med.Chem., 52, 2009
6VCG	Crystal structure of Nitrosotalea devanaterra carotenoid cleavage dioxygenase, cobalt form Descriptor: CHLORIDE ION, COBALT (II) ION, SODIUM ION, ... Authors: Daruwalla, A, Shi, W, Kiser, P.D. Deposit date: 2019-12-20 Release date: 2020-07-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase. Proc.Natl.Acad.Sci.USA, 117, 2020
3IR1	Crystal Structure of Lipoprotein GNA1946 from Neisseria meningitidis Descriptor: METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION Authors: Yang, X, Wu, Z, Wang, X, Shen, Y. Deposit date: 2009-08-21 Release date: 2009-10-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis J.Struct.Biol., 168, 2009
4IAK	Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBONATE ION, STRONTIUM ION, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-06 Release date: 2013-06-12 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IAY	Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-07 Release date: 2013-06-12 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
3VKO	Galectin-8 N-terminal domain in complex with sialyllactosamine Descriptor: CHLORIDE ION, Galectin-8, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Kamitori, S, Yoshida, H. Deposit date: 2011-11-18 Release date: 2012-09-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.08 Å) Cite: X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains Febs J., 279, 2012
3ICP	Crystal Structure of UDP-galactose 4-epimerase Descriptor: NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION Authors: Sakuraba, H, Kawai, T, Yoneda, K, Ohshima, T. Deposit date: 2009-07-18 Release date: 2010-07-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Crystal Structure of UDP-galactose 4-epimerase To be Published
6UR1	Crystal structure of ChoE S38A mutant in complex with acetate and acetylthiocholine Descriptor: ACETATE ION, ACETYLTHIOCHOLINE, ChoE, ... Authors: Pham, V.D, Shi, R. Deposit date: 2019-10-21 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism. J.Biol.Chem., 295, 2020
3FD5	Crystal structure of human selenophosphate synthetase 1 complex with AMPCP Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... Authors: Wang, K.T. Deposit date: 2008-11-25 Release date: 2009-09-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of catalytic intermediates of human selenophosphate synthetase 1. J.Mol.Biol., 390, 2009
3FK0	E. coli EPSP synthase (TIPS mutation) liganded with S3P Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE Authors: Schonbrunn, E. Deposit date: 2008-12-15 Release date: 2009-02-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
4I1N	R104A-ca1697 nanobody binding to the binary DHFR.folate complex Descriptor: Dihydrofolate reductase, FOLIC ACID, Protein ca1697 (nanobody) Authors: Oyen, D, Steyaert, J, Barlow, J.N. Deposit date: 2012-11-21 Release date: 2013-11-27 Method: X-RAY DIFFRACTION (1.888 Å) Cite: Exploring an alternative antibody interaction mechanism To be Published
3FOR	Thermolysin Complexed with BNPA (2-Benzyl-3-Nitro Propanoic Acid Amide) Descriptor: (2R)-2-benzyl-3-nitropropanamide, CALCIUM ION, DIMETHYL SULFOXIDE, ... Authors: Wang, S.-F, Jin, J.-Y, Tian, G.-R. Deposit date: 2008-12-31 Release date: 2010-01-12 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Nitro as ZBG in the inhibition of Thermolysin To be Published
6UY0	Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... Authors: Johnson, Z.L, Chen, J. Deposit date: 2019-11-09 Release date: 2020-06-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses. Elife, 9, 2020
3IF1	Crystal structure of 237mAb in complex with a GalNAc Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, Immunoglobulin heavy chain (IgG2a), Immunoglobulin light chain (IgG2a), ... Authors: Brooks, C.L, Evans, S.V, Borisova, S.N. Deposit date: 2009-07-23 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Antibody recognition of a unique tumor-specific glycopeptide antigen. Proc.Natl.Acad.Sci.USA, 107, 2010
4DME	GCN4 leucine zipper domain in a trimeric oligomerization state Descriptor: GCN4-p1 leucine zipper domain, SULFATE ION Authors: Oshaben, K.M, Salari, R, Chong, L.T, Horne, W.S. Deposit date: 2012-02-07 Release date: 2012-11-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The Native GCN4 Leucine-Zipper Domain Does Not Uniquely Specify a Dimeric Oligomerization State. Biochemistry, 51, 2012
4IAF	Room temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Gerlits, O, Kovalevsky, A. Deposit date: 2012-12-06 Release date: 2013-06-12 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
5O87	Crystal structure of wild type Aplysia californica AChBP in complex with nicotine Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dawson, A, Hunter, W.N, de Souza, J.O, Trumper, P. Deposit date: 2017-06-12 Release date: 2018-06-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6, 2019
3VWP	Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/R187S/H266N/D370Y mutant complexd with 6-aminohexanoate Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... Authors: Kawashima, Y, Shibata, N, Negoro, S, Higuchi, Y. Deposit date: 2012-08-30 Release date: 2013-10-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural, kinetic and theoretical analyses of hydrolase mutants altering in the directionality and equilibrium point of reversible amide-synthetic/hydrolytic reaction to be published
4HJK	U7Ub7 Disulfide variant Descriptor: PHOSPHATE ION, Ubiquitin Authors: Murray, J.M, Rouge, L. Deposit date: 2012-10-12 Release date: 2012-11-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.784 Å) Cite: Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
6SMY	Crystal structure of SLA Reductase YihU from E. Coli with NADH and product DHPS Descriptor: (2~{S})-2,3-bis(oxidanyl)propane-1-sulfonic acid, 3-sulfolactaldehyde reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Sharma, M, Davies, G.J. Deposit date: 2019-08-23 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Dynamic Structural Changes Accompany the Production of Dihydroxypropanesulfonate by Sulfolactaldehyde Reductase Acs Catalysis, 2020
6SES	Tubulin-B2 complex Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. Deposit date: 2019-07-30 Release date: 2020-07-08 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence. Mol.Pharmacol., 98, 2020

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