7U5J
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![BU of 7u5j by Molmil](/molmil-images/mine/7u5j) | Cryo-EM Structure of ALDOA | Descriptor: | Fructose-bisphosphate aldolase | Authors: | Morgan, C.E, Zhang, Z, Yu, E.W. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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7U5M
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![BU of 7u5m by Molmil](/molmil-images/mine/7u5m) | Cryo-EM Structure of GAPDH | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Morgan, C.E, Zhang, Z, Yu, E.W. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.28 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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7U5H
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![BU of 7u5h by Molmil](/molmil-images/mine/7u5h) | Cryo-EM Structure of DNPEP | Descriptor: | Aspartyl aminopeptidase, ZINC ION | Authors: | Morgan, C.E, Yu, E.W, Zhang, Z. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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7U5K
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![BU of 7u5k by Molmil](/molmil-images/mine/7u5k) | Cryo-EM Structure of DPYSL2 | Descriptor: | Dihydropyrimidinase-related protein 2 | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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7U5N
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![BU of 7u5n by Molmil](/molmil-images/mine/7u5n) | |
7U5I
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![BU of 7u5i by Molmil](/molmil-images/mine/7u5i) | |
8IO9
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![BU of 8io9 by Molmil](/molmil-images/mine/8io9) | |
7U5L
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![BU of 7u5l by Molmil](/molmil-images/mine/7u5l) | Cryo-EM Structure of Ferritin | Descriptor: | FE (III) ION, Ferritin heavy chain | Authors: | Morgan, C.E, Zhang, Z, Yu, E.W. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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6I53
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![BU of 6i53 by Molmil](/molmil-images/mine/6i53) | Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ... | Authors: | Laverty, D, Desai, R, Uchanski, T, Masiulis, S, Wojciech, J.S, Malinauskas, T, Zivanov, J, Pardon, E, Steyaert, J, Miller, K.W, Aricescu, A.R. | Deposit date: | 2018-11-12 | Release date: | 2019-01-02 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the human alpha 1 beta 3 gamma 2 GABAAreceptor in a lipid bilayer. Nature, 565, 2019
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5K6J
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![BU of 5k6j by Molmil](/molmil-images/mine/5k6j) | Human Phospodiesterase 4B in complex with pyridyloxy-benzoxaborole based inhibitor | Descriptor: | 1,2-ETHANEDIOL, 6-[[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-3-yl]oxy]-5-chloranyl-2-(4-oxidanylidenepentoxy)pyridine-3-carbonitrile, MAGNESIUM ION, ... | Authors: | Rock, F.L, Zhou, Y, Sullivan, D. | Deposit date: | 2016-05-24 | Release date: | 2017-05-31 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | To be published To Be Published
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8JSP
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![BU of 8jsp by Molmil](/molmil-images/mine/8jsp) | Ulotaront(SEP-363856)-bound Serotonin 1A (5-HT1A) receptor-Gi complex | Descriptor: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, 5-hydroxytryptamine receptor 1A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | Deposit date: | 2023-06-20 | Release date: | 2023-11-15 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JV7
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![BU of 8jv7 by Molmil](/molmil-images/mine/8jv7) | Cryo-EM structure of the panda P2X7 receptor in complex with PPADS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(E)-[4-methanoyl-6-methyl-5-oxidanyl-3-(phosphonooxymethyl)pyridin-2-yl]diazenyl]benzene-1,3-disulfonic acid, P2X purinoceptor | Authors: | Sheng, D, Hattori, M. | Deposit date: | 2023-06-27 | Release date: | 2023-11-29 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists. Elife, 12, 2024
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8ODU
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![BU of 8odu by Molmil](/molmil-images/mine/8odu) | Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (amphipol) | Descriptor: | ATPase GET3, Protein GET2,Protein GET1, ZINC ION | Authors: | McDowell, M.A, Wild, K, Sinning, I. | Deposit date: | 2023-03-09 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
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8JV8
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![BU of 8jv8 by Molmil](/molmil-images/mine/8jv8) | Cryo-EM structure of the panda P2X7 receptor in complex with PPNDS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, P2X purinoceptor | Authors: | Sheng, D, Hattori, M. | Deposit date: | 2023-06-27 | Release date: | 2023-11-29 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists. Elife, 12, 2024
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8A3D
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![BU of 8a3d by Molmil](/molmil-images/mine/8a3d) | Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Faille, A, Warren, A.J, Dent, K.C. | Deposit date: | 2022-06-08 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | The chemical landscape of the human ribosome at 1.67 angstrom resolution. Biorxiv, 2023
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2O5J
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8AMX
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![BU of 8amx by Molmil](/molmil-images/mine/8amx) | AQP7 dimer of tetramers_D4 | Descriptor: | Aquaporin-7 | Authors: | Huang, P, Venskutonyte, R, Fan, X, Li, P, Yan, N, Gourdon, P, Lindkvist-Petersson, K. | Deposit date: | 2022-08-04 | Release date: | 2023-02-15 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Cryo-EM structure supports a role of AQP7 as a junction protein. Nat Commun, 14, 2023
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8AMW
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![BU of 8amw by Molmil](/molmil-images/mine/8amw) | AQP7 dimer of tetramers_C1 | Descriptor: | Aquaporin-7, GLYCEROL | Authors: | Huang, P, Venskutonyte, R, Fan, X, Li, P, Yan, N, Gourdon, P, Lindkvist-Petersson, K. | Deposit date: | 2022-08-04 | Release date: | 2023-02-15 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure supports a role of AQP7 as a junction protein. Nat Commun, 14, 2023
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8R8L
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4KP6
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![BU of 4kp6 by Molmil](/molmil-images/mine/4kp6) | Crystal structure of human phosphodiesterase 4B (PDE4B) in complex with a [1,3,5]triazine derivative | Descriptor: | 1,2-ETHANEDIOL, 2-ethyl-2-{[4-(methylamino)-6-(1H-1,2,4-triazol-1-yl)-1,3,5-triazin-2-yl]amino}butanenitrile, MAGNESIUM ION, ... | Authors: | Gewald, R, Grunwald, C, Egerland, U. | Deposit date: | 2013-05-13 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of triazines as potent, selective and orally active PDE4 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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8QRH
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![BU of 8qrh by Molmil](/molmil-images/mine/8qrh) | Inactivated tick-borne encephalitis virus (TBEV) vaccine strain Sofjin-Chumakov | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, Small envelope protein M | Authors: | Moiseenko, A.V, Zhang, Y, Vorovitch, M, Ivanova, A, Liu, Z, Osolodkin, D.I, Egorov, A, Ishmukhametov, A, Sokolova, O.S. | Deposit date: | 2023-10-07 | Release date: | 2024-06-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The structure of inactivated mature tick-borne encephalitis virus at 3.0 angstrom resolution. Emerg Microbes Infect, 13, 2024
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1OYN
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![BU of 1oyn by Molmil](/molmil-images/mine/1oyn) | Crystal structure of PDE4D2 in complex with (R,S)-rolipram | Descriptor: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | Authors: | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | Deposit date: | 2003-04-05 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity Structure, 11, 2003
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5JPW
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![BU of 5jpw by Molmil](/molmil-images/mine/5jpw) | Molecular basis for protein recognition specificity of the DYNLT1/Tctex1 canonical binding groove. Characterization of the interaction with activin receptor IIB | Descriptor: | Dynein light chain Tctex-type 1,Cytoplasmic dynein 1 intermediate chain 2 | Authors: | Rodriguez-Crespo, I, Merino-Gracia, J, Bruix, M, Zamora-Carreras, H. | Deposit date: | 2016-05-04 | Release date: | 2016-08-17 | Last modified: | 2024-07-03 | Method: | SOLUTION NMR | Cite: | Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB. J.Biol.Chem., 291, 2016
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1OXT
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![BU of 1oxt by Molmil](/molmil-images/mine/1oxt) | Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus | Descriptor: | ABC transporter, ATP binding protein | Authors: | Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M. | Deposit date: | 2003-04-03 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus:
nucleotide-free and nucleotide-bound conformations J.Mol.Biol., 330, 2003
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4NX7
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![BU of 4nx7 by Molmil](/molmil-images/mine/4nx7) | single cryogenic temperature model of DHFR | Descriptor: | BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | Fenwick, R.B, van den Bedem, H, Fraser, J.S, Wright, P.E. | Deposit date: | 2013-12-08 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR. Proc.Natl.Acad.Sci.USA, 111, 2014
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