8JSP

Ulotaront(SEP-363856)-bound Serotonin 1A (5-HT1A) receptor-Gi complex

Summary for 8JSP

• Entry DOI: 10.2210/pdb8jsp/pdb
• EMDB information: 36626
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... (6 entities in total)
• Functional Keywords: complex, agonist, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 149877.86

Authors

Xu, Z.,Guo, L.L.,Zhao, C.,Shen, S.Y.,Sun, J.P.,Shao, Z.H. (deposition date: 2023-06-20, release date: 2023-11-15, Last modification date: 2024-01-03)

• Primary citation: Xu, Z.,Guo, L.,Yu, J.,Shen, S.,Wu, C.,Zhang, W.,Zhao, C.,Deng, Y.,Tian, X.,Feng, Y.,Hou, H.,Su, L.,Wang, H.,Guo, S.,Wang, H.,Wang, K.,Chen, P.,Zhao, J.,Zhang, X.,Yong, X.,Cheng, L.,Liu, L.,Yang, S.,Yang, F.,Wang, X.,Yu, X.,Xu, Y.,Sun, J.P.,Yan, W.,Shao, Z.; Ligand recognition and G-protein coupling of trace amine receptor TAAR1.; Nature, 624:672-681, 2023; PubMed: 37935376; DOI: 10.1038/s41586-023-06804-z

Experimental method

ELECTRON MICROSCOPY (3.65 Å)