1OYN

Crystal structure of PDE4D2 in complex with (R,S)-rolipram

Summary for 1OYN

• Entry DOI: 10.2210/pdb1oyn/pdb
• Related: 1OYM
• Descriptor: cAMP-specific phosphodiesterase PDE4D2, ZINC ION, ROLIPRAM, ... (4 entities in total)
• Functional Keywords: pde, camp, rolipram, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q08499
• Total number of polymer chains: 4
• Total formula weight: 167203.74

Authors

Huai, Q.,Wang, H.,Sun, Y.,Kim, H.Y.,Liu, Y.,Ke, H. (deposition date: 2003-04-05, release date: 2003-07-15, Last modification date: 2024-02-14)

• Primary citation: Huai, Q.,Wang, H.,Sun, Y.,Kim, H.Y.,Liu, Y.,Ke, H.; Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity; Structure, 11:865-873, 2003; PubMed: 12842049; DOI: 10.1016/S0969-2126(03)00123-0

Experimental method

X-RAY DIFFRACTION (2 Å)