1OYN

Crystal structure of PDE4D2 in complex with (R,S)-rolipram

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	cAMP-specific phosphodiesterase PDE4D2	polymer	360	41394.8	4	UniProt (Q08499) Pfam (PF00233)	Homo sapiens (human)	DPDE3, PDE43, PDE4D2
2	E, F, H, I, K... (A, B, C, D)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	G, J, M, P (A, B, C, D)	ROLIPRAM	non-polymer		275.3	4	Chemie (ROL)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	173	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	165579.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1624.6
All*	Total formula weight	167203.7

*Water molecules are not included.