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1G7D
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BU of 1g7d by Molmil
NMR STRUCTURE OF ERP29 C-DOMAIN
Descriptor: ENDOPLASMIC RETICULUM PROTEIN ERP29
Authors:Liepinsh, E, Mkrtchian, S, Barishev, M, Sharipo, A, Ingelman-Sundberg, M, Otting, G.
Deposit date:2000-11-10
Release date:2000-11-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer.
Structure, 9, 2001
1EJA
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BU of 1eja by Molmil
STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR
Descriptor: BDELLASTASIN, SODIUM ION, TRYPSIN
Authors:Rester, U, Moser, M, Huber, R, Bode, W.
Deposit date:2000-03-02
Release date:2001-03-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin.
Acta Crystallogr.,Sect.D, 56, 2000
8ARY
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BU of 8ary by Molmil
Small molecular stabilizer for ERalpha and 14-3-3 (1080273)
Descriptor: 14-3-3 protein sigma, 2-chloranyl-N-[[1-[1-(4-chloranylphenoxy)cyclohexyl]carbonylpiperidin-4-yl]methyl]ethanamide, Estrogen receptor, ...
Authors:Visser, E.J, Vandenboorn, E.M.F, Ottmann, C.
Deposit date:2022-08-17
Release date:2023-09-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3 sigma /ER alpha Protein-Protein Interaction from Nonselective Fragments.
J.Am.Chem.Soc., 145, 2023
8ZEQ
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BU of 8zeq by Molmil
Molecular Architecture of Human Glycogen Debranching Enzyme: Insights into Glycogen Storage Disease III Pathogenesis
Descriptor: Glycogen debranching enzyme
Authors:Guan, H, Chen, H.
Deposit date:2024-05-06
Release date:2025-05-14
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular Architecture of Human Glycogen Debranching Enzyme: Insights into Glycogen Storage Disease III Pathogenesis
To Be Published
6ARY
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BU of 6ary by Molmil
Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor
Descriptor: (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R.
Deposit date:2017-08-23
Release date:2018-01-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.257 Å)
Cite:Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
9ARY
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BU of 9ary by Molmil
Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Descriptor: 5-hydroxytryptamine receptor 2A, G subunit q (Gi2-mini-Gq chimeric), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Gumpper, R.H, Fay, J.F, Roth, B.L.
Deposit date:2024-02-24
Release date:2025-04-02
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:The structural diversity of psychedelic drug actions revealed.
Nat Commun, 16, 2025
2ARY
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BU of 2ary by Molmil
Catalytic domain of Human Calpain-1
Descriptor: BETA-MERCAPTOETHANOL, CALCIUM ION, Calpain-1 catalytic subunit
Authors:Walker, J.R, Davis, T, Lunin, V, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-08-22
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
J.Mol.Biol., 366, 2007
7ARY
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BU of 7ary by Molmil
Twist-Tower_twist-corrected-variant
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2020-10-26
Release date:2020-11-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
8WBY
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BU of 8wby by Molmil
Cryo-EM structure of ACE2-B0AT1 complex with JX98
Descriptor: 2-(4-chloranyl-3,5-dimethyl-phenoxy)-~{N}-propan-2-yl-ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R, Hu, Z, Dai, L.
Deposit date:2023-09-10
Release date:2024-09-11
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Molecular basis of inhibition of the amino acid transporter B 0 AT1 (SLC6A19).
Nat Commun, 15, 2024
8WBZ
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BU of 8wbz by Molmil
Cryo-EM structure of ACE2-B0AT1 complex with JX225
Descriptor: 2-(4-bromanyl-3-methyl-phenoxy)-~{N}-propyl-ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R, Hu, Z, Dai, L.
Deposit date:2023-09-10
Release date:2024-09-11
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular basis of inhibition of the amino acid transporter B 0 AT1 (SLC6A19).
Nat Commun, 15, 2024
4ARY
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BU of 4ary by Molmil
Lepidopteran-specific toxin Cry1Ac in complex with receptor specificity determinant GalNAc
Descriptor: 1,3-DIAMINOPROPANE, 2-acetamido-2-deoxy-beta-D-galactopyranose, PESTICIDAL CRYSTAL PROTEIN CRY1AC
Authors:Derbyshire, D.J, Carroll, J, Ellar, D.J, Li, J.
Deposit date:2012-04-27
Release date:2013-05-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Basis of Galnac-Dependent Receptor Recognition by B. Thuringiensis Toxin Cry1Ac
To be Published
4ARX
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BU of 4arx by Molmil
Lepidoptera-specific toxin Cry1Ac from Bacillus thuringiensis ssp. kurstaki HD-73
Descriptor: 1,3-DIAMINOPROPANE, GLYCEROL, PESTICIDAL CRYSTAL PROTEIN CRY1AC
Authors:Derbyshire, D.J, Carroll, J, Ellar, D.J, Li, J.
Deposit date:2012-04-27
Release date:2013-05-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis of Galnac-Dependent Receptor Recognition by B. Thuringiensis Toxin Cry1Ac
To be Published
3ECS
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BU of 3ecs by Molmil
Crystal structure of human eIF2B alpha
Descriptor: CHLORIDE ION, SULFATE ION, Translation initiation factor eIF-2B subunit alpha
Authors:Hiyama, T.B, Ito, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-09-01
Release date:2009-09-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the alpha subunit of human translation initiation factor 2B
J.Mol.Biol., 392, 2009
1KMR
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BU of 1kmr by Molmil
Solution NMR Structure of Surfactant Protein B (11-25) (SP-B11-25)
Descriptor: PULMONARY SURFACTANT-ASSOCIATED PROTEIN B
Authors:Kurutz, J.W, Lee, K.Y.C.
Deposit date:2001-12-17
Release date:2002-08-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of lung surfactant peptide SP-B(11-25).
Biochemistry, 41, 2002
4V69
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BU of 4v69 by Molmil
Ternary complex-bound E.coli 70S ribosome.
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
8RCK
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BU of 8rck by Molmil
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.
Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L.
Deposit date:2023-12-06
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.
To Be Published
8RCH
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BU of 8rch by Molmil
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, overall refinement
Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L.
Deposit date:2023-12-06
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:cryoEM structure of mTORC1 with the cancer-associated 1455-EWED-1458 duplication variant, overall refinement
To Be Published
8RCN
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BU of 8rcn by Molmil
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L.
Deposit date:2023-12-06
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
To Be Published
5APO
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BU of 5apo by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
5APN
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BU of 5apn by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
4V8T
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BU of 4v8t by Molmil
Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1
Descriptor: 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ...
Authors:Greber, B.J, Boehringer, D, Montellese, C, Ban, N.
Deposit date:2012-08-07
Release date:2014-07-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 19, 2012
5XLN
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BU of 5xln by Molmil
Crystal structure of the TRS_UNE-T and 4EHP complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, Threonine--tRNA ligase, cytoplasmic
Authors:Hwang, J, Nguyen, L.T, Kim, M.H.
Deposit date:2017-05-11
Release date:2018-11-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A threonyl-tRNA synthetase-mediated translation initiation machinery.
Nat Commun, 10, 2019
8QZZ
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BU of 8qzz by Molmil
Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Yan, Y, Ron, D.
Deposit date:2023-10-30
Release date:2024-03-20
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
4UER
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BU of 4uer by Molmil
40S-eIF1-eIF1A-eIF3-eIF3j translation initiation complex from Lachancea kluyveri
Descriptor: 18S RRNA, EIF1, EIF1A, ...
Authors:Aylett, C.H.S, Boehringer, D, Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-12-18
Release date:2015-02-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.47 Å)
Cite:Structure of a Yeast 40S-Eif1-Eif1A-Eif3-Eif3J Initiation Complex
Nat.Struct.Mol.Biol., 22, 2015
5M7W
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BU of 5m7w by Molmil
Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2)
Descriptor: Eukaryotic translation initiation factor 4E, GLYCEROL, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate
Authors:Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M.
Deposit date:2016-10-28
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2)
To Be Published

238582

數據於2025-07-09公開中

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