2ARY
Catalytic domain of Human Calpain-1
Summary for 2ARY
Entry DOI | 10.2210/pdb2ary/pdb |
Descriptor | Calpain-1 catalytic subunit, CALCIUM ION, BETA-MERCAPTOETHANOL, ... (4 entities in total) |
Functional Keywords | cysteine protease, papain, calcium-dependent, thiol protease, hydrolase, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): P07384 |
Total number of polymer chains | 2 |
Total formula weight | 79551.64 |
Authors | Walker, J.R.,Davis, T.,Lunin, V.,Newman, E.M.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-08-22, release date: 2005-08-30, Last modification date: 2023-08-23) |
Primary citation | Davis, T.L.,Walker, J.R.,Finerty, P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition J.Mol.Biol., 366:216-229, 2007 Cited by PubMed: 17157313DOI: 10.1016/j.jmb.2006.11.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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