2ARY
Catalytic domain of Human Calpain-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Calpain-1 catalytic subunit | polymer | 351 | 39578.5 | 2 | UniProt (P07384) Pfam (PF00648) In PDB | Homo sapiens (human) | Calpain-1 large subunit, Calcium-activated neutral proteinase 1, CANP 1, Calpain mu-type, muCANP, Micromolar-calpain |
| 2 | A, B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
| 4 | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 360 (UniProt: P07384)
| PDB | External Database | Details |
|---|---|---|
| Met 10 | - | cloning artifact |
| Gly 11 | - | cloning artifact |
| Ser 12 | - | cloning artifact |
| Ser 13 | - | cloning artifact |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| Ser 20 | - | cloning artifact |
| Ser 21 | - | cloning artifact |
| Gly 22 | - | cloning artifact |
| Leu 23 | - | cloning artifact |
| Val 24 | - | cloning artifact |
| Pro 25 | - | cloning artifact |
| Arg 26 | - | cloning artifact |
| Gly 27 | - | cloning artifact |
| Ser 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79156.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 394.7 | |
| All* | Total formula weight | 79551.6 |
