2CJF
 
 | | TYPE II DEHYDROQUINASE INHIBITOR COMPLEX | | Descriptor: | (1S,4S,5S)-1,4,5-TRIHYDROXY-3-[3-(PHENYLTHIO)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE, ... | | Authors: | Payne, R.J, Riboldi-Tunnicliffe, A, Abell, A.D, Lapthorn, A.J, Abell, C. | | Deposit date: | 2006-03-31 | | Release date: | 2007-04-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
Chemmedchem, 2, 2007
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2CJD
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2CJG
 | | Lysine aminotransferase from M. tuberculosis in bound PMP form | | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, L-LYSINE-EPSILON AMINOTRANSFERASE | | Authors: | Tripathi, S.M, Ramachandran, R. | | Deposit date: | 2006-04-01 | | Release date: | 2006-08-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Direct Evidence for a Glutamate Switch Necessary for Substrate Recognition: Crystal Structures of Lysine Epsilon-Aminotransferase (Rv3290C) from Mycobacterium Tuberculosis H37Rv.
J.Mol.Biol., 362, 2006
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1DXR
 | | Photosynthetic reaction center from Rhodopseudomonas viridis - His L168 Phe mutant (terbutryn complex) | | Descriptor: | 15-cis-1,2-dihydroneurosporene, 2-T-BUTYLAMINO-4-ETHYLAMINO-6-METHYLTHIO-S-TRIAZINE, BACTERIOCHLOROPHYLL B, ... | | Authors: | Lancaster, C.R.D, Bibikova, M, Sabatino, P, Oesterhelt, D, Michel, H. | | Deposit date: | 2000-01-15 | | Release date: | 2001-01-12 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described at 2.00-A resolution.
J. Biol. Chem., 275, 2000
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1LEH
 | | LEUCINE DEHYDROGENASE FROM BACILLUS SPHAERICUS | | Descriptor: | LEUCINE DEHYDROGENASE | | Authors: | Baker, P.J, Turnbull, A.P, Sedelnikova, S.E, Stillman, T.J, Rice, D.W. | | Deposit date: | 1995-06-09 | | Release date: | 1996-12-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A role for quaternary structure in the substrate specificity of leucine dehydrogenase.
Structure, 3, 1995
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2C7B
 | | The Crystal Structure of EstE1, a New Thermophilic and Thermostable Carboxylesterase Cloned from a Metagenomic Library | | Descriptor: | CARBOXYLESTERASE | | Authors: | Byun, J.-S, Rhee, J.-K, Kim, D.-U, Oh, J.-W, Cho, H.-S. | | Deposit date: | 2005-11-21 | | Release date: | 2005-12-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Hyperthermophilic Esterase Este1 and the Relationship between its Dimerization and Thermostability Properties.
Bmc Struct.Biol., 7, 2007
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2CBQ
 | | Crystal structure of the neocarzinostatin 1Tes15 mutant bound to testosterone hemisuccinate. | | Descriptor: | NEOCARZINOSTATIN, SULFATE ION, TESTOSTERONE HEMISUCCINATE | | Authors: | Drevelle, A, Graille, M, Heyd, B, Sorel, I, Ulryck, N, Pecorari, F, Desmadril, M, Van Tilbeurgh, H, Minard, P. | | Deposit date: | 2006-01-06 | | Release date: | 2006-03-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways.
J.Mol.Biol., 358, 2006
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2CAJ
 | | NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 4 intermediary sites | | Descriptor: | CHLORIDE ION, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Dian, C, Schauer, K, Kapp, U, McSweeney, S.M, Labigne, A, Terradot, L. | | Deposit date: | 2005-12-21 | | Release date: | 2006-07-17 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States.
J.Mol.Biol., 361, 2006
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2CIN
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2CJH
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2OAR
 | | Mechanosensitive Channel of Large Conductance (MscL) | | Descriptor: | GOLD ION, Large-conductance mechanosensitive channel | | Authors: | Rees, D.C, Chang, G, Spencer, R.H, Lee, A.T, Steinbacher, S, Strop, P. | | Deposit date: | 2006-12-17 | | Release date: | 2007-01-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structures of the Prokaryotic Mechanosensitive Channels MscL and MscS
Current Topics in Membranes, 58, 2007
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2DM5
 | | Thermodynamic Penalty Arising From Burial of a Ligand Polar Group Within a Hydrophobic Pocket of a Protein Receptor | | Descriptor: | CADMIUM ION, Major Urinary Protein, OCTANE-1,8-DIOL | | Authors: | Barratt, E, Bronowska, A, Vondrasek, J, Bingham, R, Phillips, S, Homans, S.W. | | Deposit date: | 2006-04-20 | | Release date: | 2006-10-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Thermodynamic penalty arising from burial of a ligand polar group within a hydrophobic pocket of a protein receptor
J.Mol.Biol., 362, 2006
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1CSR
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1FSP
 | | NMR SOLUTION STRUCTURE OF BACILLUS SUBTILIS SPO0F PROTEIN, 20 STRUCTURES | | Descriptor: | STAGE 0 SPORULATION PROTEIN F | | Authors: | Feher, V.A, Skelton, N.J, Dahlquist, F.W, Cavanagh, J. | | Deposit date: | 1997-06-05 | | Release date: | 1997-12-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, Spo0F: implications for phosphorylation and molecular recognition.
Biochemistry, 36, 1997
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2E3X
 | | Crystal structure of Russell's viper venom metalloproteinase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, ... | | Authors: | Igarashi, T, Takeda, S. | | Deposit date: | 2006-11-30 | | Release date: | 2007-12-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Crystal structure of RVV-X: an example of evolutionary gain of specificity by ADAM proteinases.
Febs Lett., 581, 2007
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1PJ4
 | | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, ATP, Mn++, and allosteric activator fumarate. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-MALATE, FUMARIC ACID, ... | | Authors: | Tao, X, Yang, Z, Tong, L. | | Deposit date: | 2003-05-31 | | Release date: | 2003-09-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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1PJ2
 | | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate | | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FUMARIC ACID, ... | | Authors: | Tao, X, Yang, Z, Tong, L. | | Deposit date: | 2003-05-30 | | Release date: | 2003-11-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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2E11
 | | The Crystal Structure of XC1258 from Xanthomonas campestris: A CN-hydrolase Superfamily Protein with an Arsenic Adduct in the Active Site | | Descriptor: | CACODYLATE ION, Hydrolase | | Authors: | Chin, K.-H, Tsai, Y.-D, Chan, N.-L, Huang, K.-F, Wang, A.H.-J, Chou, S.-H. | | Deposit date: | 2006-10-17 | | Release date: | 2007-08-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | The crystal structure of XC1258 from Xanthomonas campestris: A putative procaryotic Nit protein with an arsenic adduct in the active site
Proteins, 69, 2007
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5TLQ
 | | Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex | | Descriptor: | 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA | | Authors: | Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S. | | Deposit date: | 2016-10-11 | | Release date: | 2017-04-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.
PLoS ONE, 12, 2017
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1PJ3
 | | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate. | | Descriptor: | FUMARIC ACID, MANGANESE (II) ION, NAD-dependent malic enzyme, ... | | Authors: | Tao, X, Yang, Z, Tong, L. | | Deposit date: | 2003-05-30 | | Release date: | 2003-11-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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2LKX
 | | NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site | | Descriptor: | DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), Pituitary homeobox 3 | | Authors: | Baird-Titus, J.M, Doerdelmann, T, Chaney, B.A, Clark-Baldwin, K, Dave, V, Ma, J. | | Deposit date: | 2011-10-21 | | Release date: | 2012-05-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome
Biochemistry, 44, 2005
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2EGH
 | | Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with a magnesium ion, NADPH and fosmidomycin | | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MAGNESIUM ION, ... | | Authors: | Yajima, S, Hara, K, Iino, D, Sasaki, Y, Kuzuyama, T, Seto, H. | | Deposit date: | 2007-03-01 | | Release date: | 2007-06-19 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin
Acta Crystallogr.,Sect.F, 63, 2007
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2E4E
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2Q0Q
 | | Structure of the Native M. Smegmatis Aryl Esterase | | Descriptor: | GLYCEROL, SULFATE ION, aryl esterase | | Authors: | Mathews, I.I, Soltis, M, Saldajeno, M, Ganshaw, G, Sala, R, Weyler, W, Cervin, M.A, Whited, G, Bott, R. | | Deposit date: | 2007-05-22 | | Release date: | 2007-12-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a novel enzyme that catalyzes acyl transfer to alcohols in aqueous conditions.
Biochemistry, 46, 2007
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1EP8
 | | CRYSTAL STRUCTURE OF A MUTATED THIOREDOXIN, D30A, FROM CHLAMYDOMONAS REINHARDTII | | Descriptor: | THIOREDOXIN CH1, H-TYPE | | Authors: | Menchise, V, Corbier, C, Didierjean, C, Saviano, M, Benedetti, E, Jacquot, J.P, Aubry, A. | | Deposit date: | 2000-03-28 | | Release date: | 2001-12-12 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism.
Biochem.J., 359, 2001
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