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PDB: 4 results
8DLF
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BU of 8dlf by Molmil
EBNA1 DNA binding domain (DBD) (458-617)+2 repeats of family repeat (FR) region
Descriptor: 2XFR DNA (56-MER), Epstein-Barr nuclear antigen 1
Authors:Mei, Y, Lieberman, P.M, Murakami, K.
Deposit date:2022-07-07
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Cryo-EM Structure and Functional Studies of EBNA1 Binding to the Family of Repeats and Dyad Symmetry Elements of Epstein-Barr Virus oriP.
J.Virol., 96, 2022
6VH6
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BU of 6vh6 by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragment
Descriptor: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E, Lieberman, P.M.
Deposit date:2020-01-09
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Molecules, 25, 2020
5T7X
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BU of 5t7x by Molmil
Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
Descriptor: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
Authors:Malecka, K.A, Messick, T.E, Lieberman, P.M.
Deposit date:2016-09-06
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017
6PW2
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BU of 6pw2 by Molmil
Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication
Descriptor: DNA (62-MER), DNA (62-MER) complementary DNA strand, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E, Malecka, K.A, Lieberman, P.M.
Deposit date:2019-07-22
Release date:2019-08-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
J.Virol., 93, 2019

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