1VFP
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8DK2
| CryoEM structure of Pseudomonas aeruginosa PA14 JetABC in an unclamped state trapped in ATP dependent dimeric form | Descriptor: | DNA (26-MER), JetA, JetB, ... | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-07-01 | Release date: | 2022-10-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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6U6Q
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8TO8
| Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Darst, S.A, Saecker, R.M, Mueller, A.U. | Deposit date: | 2023-08-03 | Release date: | 2024-07-03 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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6O7H
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3C1M
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3C3O
| ALIX Bro1-domain:CHMIP4A co-crystal structure | Descriptor: | Charged multivesicular body protein 4a peptide, GLYCEROL, Programmed cell death 6-interacting protein | Authors: | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | Deposit date: | 2008-01-28 | Release date: | 2008-06-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2FM0
| Crystal structure of PDE4D in complex with L-869298 | Descriptor: | (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-06 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
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2FM5
| Crystal structure of PDE4D2 in complex with inhibitor L-869299 | Descriptor: | (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-07 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
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3C3R
| ALIX BRO1 CHMP4C complex | Descriptor: | Charged multivesicular body protein 4c peptide, GLYCEROL, Programmed cell death 6-interacting protein | Authors: | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | Deposit date: | 2008-01-28 | Release date: | 2008-06-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3CAY
| Crystal structure of Lipopeptide Detergent (LPD-12) | Descriptor: | DODECYL-BETA-D-MALTOSIDE, LPD-12 | Authors: | Ho, D.N, Pomroy, N.C, Cuesta-Seijo, J.A, Prive, G.G. | Deposit date: | 2008-02-20 | Release date: | 2008-09-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of a self-assembling lipopeptide detergent at 1.20 A. Proc.Natl.Acad.Sci.USA, 105, 2008
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2G1K
| Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimate at 1.75 angstrom resolution | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, CHLORIDE ION, SULFATE ION, ... | Authors: | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | Deposit date: | 2006-02-14 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue. Biochemistry, 45, 2006
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3ZX2
| NTPDase1 in complex with Decavanadate | Descriptor: | ACETIC ACID, CHLORIDE ION, DECAVANADATE, ... | Authors: | Zebisch, M, Schaefer, P, Straeter, N. | Deposit date: | 2011-08-04 | Release date: | 2011-11-30 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1. J.Mol.Biol., 415, 2012
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2ACG
| ACANTHAMOEBA CASTELLANII PROFILIN II | Descriptor: | PROFILIN II | Authors: | Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C. | Deposit date: | 1994-08-30 | Release date: | 1994-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates. Proc.Natl.Acad.Sci.USA, 91, 1994
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4UQQ
| Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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6UJV
| Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) | Descriptor: | Envelope glycoprotein GP41 | Authors: | Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. | Deposit date: | 2019-10-03 | Release date: | 2020-05-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nat Commun, 11, 2020
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6DJ8
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3GWT
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8DNP
| Human Brain Ferritin Heavy Chain | Descriptor: | FE (III) ION, Ferritin heavy chain | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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8DNU
| Human Brain Glutamine Synthetase | Descriptor: | Glutamine synthetase, MANGANESE (II) ION | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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8DNO
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8DNS
| Human Brain Glyceraldehyde 3-phosphate dehydrogenase | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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8DNM
| Human Brain Dihydropyrimidinase-related protein 2 | Descriptor: | Dihydropyrimidinase-related protein 2 | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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5LG7
| Solution NMR structure of Tryptophan to Arginine mutant of Arkadia RING domain | Descriptor: | E3 ubiquitin-protein ligase Arkadia, ZINC ION | Authors: | Birkou, M, Chasapis, C.T, Loutsidou, A.K, Bentrop, D, Lelli, M, Herrmann, T, Episkopou, V, Spyroulias, G.A. | Deposit date: | 2016-07-06 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity. J. Mol. Biol., 429, 2017
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3HIF
| The crystal structure of apo wild type CAP at 3.6 A resolution. | Descriptor: | Catabolite gene activator | Authors: | Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S. | Deposit date: | 2009-05-19 | Release date: | 2009-09-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding. Proc.Natl.Acad.Sci.USA, 106, 2009
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