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1N5K
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE (RESOLUTION 2.1 A)
Descriptor: ACETATE ION, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ...
Authors:Fioravanti, E, Haouz, A, Ursby, T, Munier-Lehmann, H, Delarue, M, Bourgeois, D.
Deposit date:2002-11-06
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway
J.Mol.Biol., 375, 2003
1N5L
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE, AFTER CATALYSIS IN THE CRYSTAL (2.3 A RESOLUTION)
Descriptor: ACETATE ION, DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Fioravanti, E, Haouz, A, Ursby, T, Munier-Lehmann, H, Delarue, M, Bourgeois, D.
Deposit date:2002-11-06
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway
J.Mol.Biol., 375, 2003
1NPD
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BU of 1npd by Molmil
X-RAY STRUCTURE OF SHIKIMATE DEHYDROGENASE COMPLEXED WITH NAD+ FROM E.COLI (YDIB) NORTHEAST STRUCTURAL GENOMICS RESEARCH CONSORTIUM (NESG) TARGET ER24
Descriptor: HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Benach, J, Kuzin, A.P, Lee, I, Rost, B, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-01-17
Release date:2003-01-28
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase
J.Biol.Chem., 278, 2003
2HNH
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BU of 2hnh by Molmil
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Meindert, M.H, Georgescu, R.E, Lee, S, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-12
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
2HPI
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BU of 2hpi by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
Descriptor: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ...
Authors:Bailey, S, Wing, R.A, Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
1PVG
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BU of 1pvg by Molmil
Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II
Descriptor: DNA topoisomerase II, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Classen, S, Olland, S, Berger, J.M.
Deposit date:2003-06-27
Release date:2003-08-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Proc.Natl.Acad.Sci.USA, 100, 2003
1PRG
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BU of 1prg by Molmil
LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Descriptor: PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)
Authors:Nolte, R.T, Wisely, G.B, Milburn, M.V.
Deposit date:1998-07-02
Release date:2001-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.
Nature, 395, 1998
2K8J
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BU of 2k8j by Molmil
Solution structure of HCV p7 tm2
Descriptor: p7tm2
Authors:Montserret, R, Penin, F.
Deposit date:2008-09-12
Release date:2009-01-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure and ion channel activity of the p7 protein from hepatitis C virus.
J.Biol.Chem., 285, 2010
2GPL
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BU of 2gpl by Molmil
TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors
Descriptor: BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M.
Deposit date:2006-04-18
Release date:2006-07-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome.
Chem.Biol., 13, 2006
1QZR
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BU of 1qzr by Molmil
CRYSTAL STRUCTURE OF THE ATPASE REGION OF SACCHAROMYCES CEREVISIAE TOPOISOMERASE II BOUND TO ICRF-187 (DEXRAZOXANE)
Descriptor: (S)-4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-2,6-PIPERAZINEDIONE, DNA topoisomerase II, MAGNESIUM ION, ...
Authors:Classen, S, Olland, S, Berger, J.M.
Deposit date:2003-09-17
Release date:2003-09-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Proc.Natl.Acad.Sci.USA, 100, 2003
3EIV
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BU of 3eiv by Molmil
Crystal Structure of Single-stranded DNA-binding protein from Streptomyces coelicolor
Descriptor: Single-stranded DNA-binding protein 2
Authors:Luic, M, Stefanic, Z, Vujaklija, D.
Deposit date:2008-09-17
Release date:2009-09-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structure of the single-stranded DNA-binding protein from Streptomyces coelicolor.
Acta Crystallogr.,Sect.D, 65, 2009
3EQL
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BU of 3eql by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I.
Deposit date:2008-09-30
Release date:2008-10-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Transcription inactivation through local refolding of the RNA polymerase structure.
Nature, 457, 2009
1HK7
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BU of 1hk7 by Molmil
Middle Domain of HSP90
Descriptor: CADMIUM ION, HEAT SHOCK PROTEIN HSP82, MAGNESIUM ION
Authors:Meyer, P, Prodromou, C, Roe, S.M, Pearl, L.H.
Deposit date:2003-03-06
Release date:2004-01-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Analysis of the Middle Segment of Hsp90. Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions
Mol.Cell, 11, 2003
3FKI
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BU of 3fki by Molmil
12-Subunit RNA Polymerase II Refined with Zn-SAD data
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Meyer, P.A, Ye, P, Suh, M.H, Zhang, M, Fu, J.
Deposit date:2008-12-16
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
J.Biol.Chem., 284, 2009
3CW4
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BU of 3cw4 by Molmil
Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2
Descriptor: Polymerase basic protein 2
Authors:Kuzuhara, T, Kise, D, Yoshida, H, Horita, T, Murasaki, Y, Utsunomiya, H, Fujiki, H, Tsuge, H.
Deposit date:2008-04-21
Release date:2009-01-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
J.Biol.Chem., 284, 2009
1JO6
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BU of 1jo6 by Molmil
Solution structure of the cytoplasmic N-terminus of the BK beta-subunit KCNMB2
Descriptor: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Authors:Bentrop, D, Beyermann, M, Wissmann, R, Fakler, B.
Deposit date:2001-07-27
Release date:2001-11-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channels.
J.Biol.Chem., 276, 2001
7ZY9
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BU of 7zy9 by Molmil
Structure of D165A/D167A double mutant of Chit33 from Trichoderma harzianum complexed with chitintetraose.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endochitinase 33
Authors:Jimenez-Ortega, E, Sanz-Aparicio, J.
Deposit date:2022-05-24
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Function Insights into the Fungal Endo -Chitinase Chit33 Depict its Mechanism on Chitinous Material.
Int J Mol Sci, 23, 2022
7ZYA
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BU of 7zya by Molmil
Structure of Chit33 from Trichoderma harzianum.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Endochitinase 33, ...
Authors:Jimenez-Ortega, E, Sanz-Aparicio, J.
Deposit date:2022-05-24
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structure-Function Insights into the Fungal Endo -Chitinase Chit33 Depict its Mechanism on Chitinous Material.
Int J Mol Sci, 23, 2022
1KN7
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BU of 1kn7 by Molmil
Solution structure of the tandem inactivation domain (residues 1-75) of potassium channel RCK4 (Kv1.4)
Descriptor: VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4
Authors:Wissmann, R, Bildl, W, Oliver, D, Beyermann, M, Kalbitzer, H.R, Bentrop, D, Fakler, B.
Deposit date:2001-12-18
Release date:2003-05-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure and Function of the "Tandem Inactivation Domain" of the Neuronal A-type Potassium Channel Kv1.4
J.Biol.Chem., 278, 2003
1KXP
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CRYSTAL STRUCTURE OF HUMAN VITAMIN D-BINDING PROTEIN IN COMPLEX WITH SKELETAL ACTIN
Descriptor: ACTIN,ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, HUMAN VITAMIN D-BINDING PROTEIN, ...
Authors:Otterbein, L.R, Dominguez, R.
Deposit date:2002-02-01
Release date:2002-06-19
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
Proc.Natl.Acad.Sci.USA, 99, 2002
3ETO
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BU of 3eto by Molmil
2 Angstrom Xray structure of the NOTCH1 Negative Regulatory Region (NRR)
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gordon, W.R, Blacklow, S.C.
Deposit date:2008-10-08
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Blood, 113, 2009
1KW2
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BU of 1kw2 by Molmil
CRYSTAL STRUCTURE OF UNCOMPLEXED VITAMIN D-BINDING PROTEIN
Descriptor: Vitamin D-binding protein
Authors:Otterbein, L.R, Dominguez, R.
Deposit date:2002-01-28
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
Proc.Natl.Acad.Sci.USA, 99, 2002
3F95
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Crystal Structure of Extra C-terminal Domain (X) of Exo-1,3/1,4-beta-glucanase (ExoP) from Pseudoalteromonas sp. BB1
Descriptor: Beta-glucosidase, CHLORIDE ION
Authors:Nakatani, Y, Cutfield, S.M, Cutfield, J.F.
Deposit date:2008-11-13
Release date:2009-11-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and activity of exo-1,3/1,4-beta-glucanase from marine bacterium Pseudoalteromonas sp. BB1 showing a novel C-terminal domain
Febs J., 2011
1ISQ
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BU of 1isq by Molmil
Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide
Descriptor: Proliferating Cell Nuclear Antigen, replication factor C large subunit
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2001-12-19
Release date:2002-10-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
Genes Cells, 7, 2002
1L3E
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BU of 1l3e by Molmil
NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex
Descriptor: ZINC ION, hypoxia inducible factor-1 alpha subunit, p300 protein
Authors:Freedman, S.J, Sun, Z.J, Poy, F, Kung, A.L, Livingston, D.M, Wagner, G, Eck, M.J.
Deposit date:2002-02-26
Release date:2002-04-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
Proc.Natl.Acad.Sci.USA, 99, 2002

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數據於2024-10-09公開中

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