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7JVG
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Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol
Descriptor: (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Retinol-binding protein 2
Authors:Silvaroli, J.A, Golczak, M.
Deposit date:2020-08-21
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7JVY
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Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether
Descriptor: 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol, Retinol-binding protein 2
Authors:Silvaroli, J.A, Banarjee, S, Golczak, M.
Deposit date:2020-08-24
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7JZ5
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BU of 7jz5 by Molmil
Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachodonoyl-1-thio-glycerol
Descriptor: Retinol-binding protein 2, S-[(2R)-2,3-dihydroxypropyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate
Authors:Silvaroli, J.A, Banarjee, S, Golczak, M.
Deposit date:2020-09-01
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.567 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7LHJ
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Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal
Descriptor: ACETATE ION, GLYCEROL, RETINAL, ...
Authors:Ehyaei, N, Geiger, J.H, Borhan, B.
Deposit date:2021-01-25
Release date:2021-02-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15cis- retinal
To Be Published
7KP5
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Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin
Descriptor: Beta-lactoglobulin, DODECYL SULFATE
Authors:Rodriguez-Hernandez, A, Rodriguez-Romero, A.
Deposit date:2020-11-10
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Energetic and structural effects of the Tanford transition on ligand recognition of bovine beta-lactoglobulin.
Arch.Biochem.Biophys., 699, 2021
7LHN
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Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light
Descriptor: GLYCEROL, RETINAL, Retinol-binding protein 2
Authors:Ehyaei, N, Geiger, J.H, Borhan, B.
Deposit date:2021-01-25
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light
To Be Published
7LHM
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Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal
Descriptor: ACETATE ION, GLYCEROL, RETINAL, ...
Authors:Ehyaei, N, Geiger, J.H, Borhan, B.
Deposit date:2021-01-25
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal
To Be Published
7LHO
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Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark
Descriptor: GLYCEROL, RETINAL, Retinol-binding protein 2
Authors:Ehyaei, N, Geiger, J.H, Borhan, B.
Deposit date:2021-01-26
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark
To Be Published
7LWC
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BU of 7lwc by Molmil
Goat beta-lactoglobulin mutant Q59A
Descriptor: Beta-lactoglobulin
Authors:Munoz, D.A, Dobson, R.C.J.
Deposit date:2021-02-28
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Engineering food proteins for improved digestibility and lower allergenicity: a case study using caprine beta-lactoglobulin
To Be Published
7KOT
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BU of 7kot by Molmil
Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin
Descriptor: Beta-lactoglobulin, DODECYL SULFATE
Authors:Rodriguez-Hernandez, A, Rodriguez-Romero, A.
Deposit date:2020-11-09
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Energetic and structural effects of the Tanford transition on ligand recognition of bovine beta-lactoglobulin.
Arch.Biochem.Biophys., 699, 2021
6QBA
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BU of 6qba by Molmil
Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand A1120 and engineered binding scaffold
Descriptor: 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Mlynek, G, Brey, C.U, Djinovic-Carugo, K, Puehringer, D.
Deposit date:2018-12-20
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conformation-specific ON-switch for controlling CAR T cells with an orally available drug.
Proc.Natl.Acad.Sci.USA, 117, 2020
6S8V
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BU of 6s8v by Molmil
Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain
Descriptor: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin
Authors:Schiefner, A, Deuschle, F.-C, Skerra, A.
Deposit date:2019-07-10
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications.
Theranostics, 10, 2020
6SUA
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Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain
Descriptor: 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin, SULFATE ION
Authors:Schiefner, A, Deuschle, F.-C, Skerra, A.
Deposit date:2019-09-13
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.
Protein Sci., 29, 2020
3BSZ
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BU of 3bsz by Molmil
Crystal structure of the transthyretin-retinol binding protein-Fab complex
Descriptor: Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ...
Authors:Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R.
Deposit date:2007-12-27
Release date:2008-11-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
Febs J., 275, 2008
1RLB
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BU of 1rlb by Molmil
RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN
Descriptor: RETINOIC ACID, RETINOL BINDING PROTEIN, TRANSTHYRETIN
Authors:Monaco, H.L, Rizzi, M, Coda, A.
Deposit date:1995-02-20
Release date:1996-04-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein.
Science, 268, 1995
2WQA
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BU of 2wqa by Molmil
Complex of TTR and RBP4 and Oleic Acid
Descriptor: OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ...
Authors:Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J.
Deposit date:2009-08-14
Release date:2010-09-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr
To be Published
2RD7
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BU of 2rd7 by Molmil
Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins
Descriptor: CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain
Authors:Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M.
Deposit date:2007-09-21
Release date:2008-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
4MVL
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BU of 4mvl by Molmil
Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40
Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
Authors:Eichinger, A, Skerra, A.
Deposit date:2013-09-24
Release date:2015-08-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
4MVI
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BU of 4mvi by Molmil
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40)
Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
Authors:Eichinger, A, Skerra, A.
Deposit date:2013-09-24
Release date:2015-08-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
1QAB
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BU of 1qab by Molmil
The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP
Descriptor: PROTEIN (retinol binding protein), PROTEIN (transthyretin), RETINOL
Authors:Naylor, H.M, Newcomer, M.E.
Deposit date:1999-02-03
Release date:1999-02-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP.
Biochemistry, 38, 1999
4QAF
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BU of 4qaf by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109)
Descriptor: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ...
Authors:Giese, T, Skerra, A.
Deposit date:2014-05-04
Release date:2015-05-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold
To be Published
4QAE
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BU of 4qae by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ...
Authors:Giese, T, Skerra, A.
Deposit date:2014-05-04
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a hepcidin-binding anticalin in complex with its peptide ligand
To be Published
6H03
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BU of 6h03 by Molmil
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
6H04
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BU of 6h04 by Molmil
Closed conformation of the Membrane Attack Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
8B0H
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BU of 8b0h by Molmil
2C9, C5b9-CD59 cryoEM structure
Descriptor: CD59 glycoprotein, Complement C5, Complement component C6, ...
Authors:Couves, E.C, Gardner, S, Bubeck, D.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023

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數據於2024-07-10公開中

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