8EBH
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![BU of 8ebh by Molmil](/molmil-images/mine/8ebh) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-08-31 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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8E9A
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![BU of 8e9a by Molmil](/molmil-images/mine/8e9a) | Crystal structure of AsfvPolX in complex with 10-23 DNAzyme and Mg | Descriptor: | DNA/RNA (52-MER), MAGNESIUM ION, Repair DNA polymerase X, ... | Authors: | Cramer, E.R, Robart, A.R, Kaya, A.I. | Deposit date: | 2022-08-26 | Release date: | 2023-06-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation. Commun Chem, 6, 2023
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1EZP
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![BU of 1ezp by Molmil](/molmil-images/mine/1ezp) | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS | Descriptor: | MALTODEXTRIN BINDING PERIPLASMIC PROTEIN | Authors: | Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E. | Deposit date: | 2000-05-11 | Release date: | 2001-05-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. J.Mol.Biol., 300, 2000
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8YBE
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![BU of 8ybe by Molmil](/molmil-images/mine/8ybe) | Cryo-EM structure of Maltose Binding Protein | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Yoo, Y, Park, K, Kim, H. | Deposit date: | 2024-02-13 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Atomic resolution structure of MBP using Cryo-EM To Be Published
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2NVU
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![BU of 2nvu by Molmil](/molmil-images/mine/2nvu) | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | Authors: | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | Deposit date: | 2006-11-13 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Nature, 445, 2007
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2OBG
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![BU of 2obg by Molmil](/molmil-images/mine/2obg) | |
5WQ6
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![BU of 5wq6 by Molmil](/molmil-images/mine/5wq6) | Crystal Structure of hMNDA-PYD with MBP tag | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MBP tagged hMNDA-PYD, ... | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-23 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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1DBN
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![BU of 1dbn by Molmil](/molmil-images/mine/1dbn) | MAACKIA AMURENSIS LEUKOAGGLUTININ (LECTIN) WITH SIALYLLACTOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Imberty, A, Gautier, C, Lescar, J, Loris, R. | Deposit date: | 1999-11-03 | Release date: | 2000-06-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | An unusual carbohydrate binding site revealed by the structures of two Maackia amurensis lectins complexed with sialic acid-containing oligosaccharides. J.Biol.Chem., 275, 2000
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3PY7
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![BU of 3py7 by Molmil](/molmil-images/mine/3py7) | |
6EG3
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![BU of 6eg3 by Molmil](/molmil-images/mine/6eg3) | Crystal structure of human BRM in complex with compound 15 | Descriptor: | 3-[(4-{[(2-chloropyridin-4-yl)carbamoyl]amino}pyridin-2-yl)ethynyl]benzoic acid, ETHANOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2 | Authors: | Zhu, X, Kulathila, R, Hu, T, Xie, X. | Deposit date: | 2018-08-17 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J. Med. Chem., 61, 2018
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3M9S
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![BU of 3m9s by Molmil](/molmil-images/mine/3m9s) | Crystal structure of respiratory complex I from Thermus thermophilus | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Efremov, R.G, Baradaran, R, Sazanov, L.A. | Deposit date: | 2010-03-22 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | The architecture of respiratory complex I Nature, 465, 2010
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1DNP
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![BU of 1dnp by Molmil](/molmil-images/mine/1dnp) | STRUCTURE OF DEOXYRIBODIPYRIMIDINE PHOTOLYASE | Descriptor: | 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, DNA PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Park, H.-W, Sancar, A, Deisenhofer, J. | Deposit date: | 1995-07-03 | Release date: | 1996-08-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of DNA photolyase from Escherichia coli. Science, 268, 1995
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5V6Y
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![BU of 5v6y by Molmil](/molmil-images/mine/5v6y) | |
3MP6
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![BU of 3mp6 by Molmil](/molmil-images/mine/3mp6) | Complex Structure of Sgf29 and dimethylated H3K4 | Descriptor: | H3K4me2 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, J, Wu, M, Ruan, J, Zang, J. | Deposit date: | 2010-04-25 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
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4B3N
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![BU of 4b3n by Molmil](/molmil-images/mine/4b3n) | Crystal structure of rhesus TRIM5alpha PRY/SPRY domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ... | Authors: | Yang, H, Ji, X, Zhao, Q, Xiong, Y. | Deposit date: | 2012-07-25 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha Proc.Natl.Acad.Sci.USA, 109, 2012
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3QQV
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![BU of 3qqv by Molmil](/molmil-images/mine/3qqv) | Crystal structure of geranylgeranyl pyrophosphate synthase from corynebacterium glutamicum complexed with isoprenyl diphosphate and magnesium | Descriptor: | DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ... | Authors: | Patskovsky, Y, Toro, R, Sauder, J.M, Poulter, C.D, Gerlt, J.A, Burley, S.K, Almo, S.C, Enzyme Function Initiative (EFI), New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2011-02-16 | Release date: | 2011-03-02 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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6EG2
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![BU of 6eg2 by Molmil](/molmil-images/mine/6eg2) | Crystal structure of human BRM in complex with compound 16 | Descriptor: | ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea | Authors: | Zhu, X, Kulathila, R, Hu, T, Xie, X. | Deposit date: | 2018-08-17 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J. Med. Chem., 61, 2018
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2OOW
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![BU of 2oow by Molmil](/molmil-images/mine/2oow) | MIF Bound to a Fluorinated OXIM Derivative | Descriptor: | 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Crichlow, G.V, Al-Abed, Y, Lolis, E. | Deposit date: | 2007-01-26 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor. J.Biol.Chem., 282, 2007
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6DM8
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![BU of 6dm8 by Molmil](/molmil-images/mine/6dm8) | Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors | Descriptor: | 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog - MBP chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Zhao, B. | Deposit date: | 2018-06-04 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors. Biochemistry, 57, 2018
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6DBX
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![BU of 6dbx by Molmil](/molmil-images/mine/6dbx) | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6D66
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![BU of 6d66 by Molmil](/molmil-images/mine/6d66) | Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16 | Descriptor: | 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gumpena, R, Waugh, D.S, Lountos, G.T. | Deposit date: | 2018-04-20 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.226 Å) | Cite: | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5UVN
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![BU of 5uvn by Molmil](/molmil-images/mine/5uvn) | |
2OK2
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![BU of 2ok2 by Molmil](/molmil-images/mine/2ok2) | MutS C-terminal domain fused to Maltose Binding Protein | Descriptor: | Maltose-binding periplasmic protein, DNA mismatch repair protein mutS fusion protein, SULFATE ION, ... | Authors: | Putnam, C.D, Mendillo, M.L, Kolodner, R.D. | Deposit date: | 2007-01-15 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli MutS Tetramerization Domain Structure Reveals That Stable Dimers but Not Tetramers Are Essential for DNA Mismatch Repair in Vivo. J.Biol.Chem., 282, 2007
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5WVM
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![BU of 5wvm by Molmil](/molmil-images/mine/5wvm) | Crystal structure of baeS cocrystallized with 2 mM indole | Descriptor: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | Authors: | Wang, W, Zhang, Y, Rang, T, Xu, D. | Deposit date: | 2016-12-26 | Release date: | 2018-01-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14 Proteins, 85, 2017
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5WPZ
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![BU of 5wpz by Molmil](/molmil-images/mine/5wpz) | Crystal structure of MNDA PYD with MBP tag | Descriptor: | MBP-hMNDA-PYD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-22 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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