6QCG
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6QH1
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![BU of 6qh1 by Molmil](/molmil-images/mine/6qh1) | The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide | Descriptor: | Proliferating cell nuclear antigen, S-phase delaying protein 1 | Authors: | Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A. | Deposit date: | 2019-01-14 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide To Be Published
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5DAI
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5E0V
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2IO4
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![BU of 2io4 by Molmil](/molmil-images/mine/2io4) | Crystal structure of PCNA12 dimer from Sulfolobus solfataricus. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ... | Authors: | Hlinkova, V, Ling, H. | Deposit date: | 2006-10-09 | Release date: | 2008-04-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
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5E0T
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![BU of 5e0t by Molmil](/molmil-images/mine/5e0t) | Human PCNA mutant - S228I | Descriptor: | Proliferating cell nuclear antigen | Authors: | Duffy, C.M, Hilbert, B.J, Kelch, B.A. | Deposit date: | 2015-09-29 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6653 Å) | Cite: | A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
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8GL9
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![BU of 8gl9 by Molmil](/molmil-images/mine/8gl9) | Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE | Descriptor: | CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen | Authors: | Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J. | Deposit date: | 2023-03-21 | Release date: | 2023-07-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Small molecule targeting of transcription-replication conflict for selective chemotherapy. Cell Chem Biol, 30, 2023
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8GLA
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5DA7
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![BU of 5da7 by Molmil](/molmil-images/mine/5da7) | monomeric PCNA bound to a small protein inhibitor | Descriptor: | DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... | Authors: | Ladner, J.E, Altieri, A.S, Kelman, Z. | Deposit date: | 2015-08-19 | Release date: | 2016-05-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
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8GJ5
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![BU of 8gj5 by Molmil](/molmil-images/mine/8gj5) | fungal pcna and peptidomimetic | Descriptor: | Proliferating cell nuclear antigen, THR-ASP-ILE-ARG-ASN-PHE-PHE-HIS-SER | Authors: | Vandborg, B, Bruning, J.B. | Deposit date: | 2023-03-14 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus. J Fungi, 9, 2023
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8GJF
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![BU of 8gjf by Molmil](/molmil-images/mine/8gjf) | afupcna bound with peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B, Bruning, J.B. | Deposit date: | 2023-03-15 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus. J Fungi, 9, 2023
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8GCJ
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![BU of 8gcj by Molmil](/molmil-images/mine/8gcj) | PCNA | Descriptor: | Proliferating cell nuclear antigen | Authors: | Vandborg, B.C, Bruning, J.B. | Deposit date: | 2023-03-01 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of apo pcna To Be Published
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3GPN
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![BU of 3gpn by Molmil](/molmil-images/mine/3gpn) | Structure of the non-trimeric form of the E113G PCNA mutant protein | Descriptor: | Proliferating cell nuclear antigen | Authors: | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | Deposit date: | 2009-03-23 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
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2IJX
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3FDS
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5E0U
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2IZO
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![BU of 2izo by Molmil](/molmil-images/mine/2izo) | Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex | Descriptor: | DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ... | Authors: | Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H. | Deposit date: | 2006-07-25 | Release date: | 2006-09-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity. Nucleic Acids Res., 34, 2006
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2IX2
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![BU of 2ix2 by Molmil](/molmil-images/mine/2ix2) | Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus | Descriptor: | DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C | Authors: | Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H. | Deposit date: | 2006-07-05 | Release date: | 2006-10-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus. Acta Crystallogr.,Sect.F, 62, 2006
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3HI8
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![BU of 3hi8 by Molmil](/molmil-images/mine/3hi8) | Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii | Descriptor: | Proliferating cell nuclear antigen PcnA | Authors: | Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. | Deposit date: | 2009-05-19 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
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3F1W
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3WGW
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![BU of 3wgw by Molmil](/molmil-images/mine/3wgw) | Structure of PCNA bound to a small molecule inhibitor | Descriptor: | 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION | Authors: | Hashimoto, H. | Deposit date: | 2013-08-12 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
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3IFV
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![BU of 3ifv by Molmil](/molmil-images/mine/3ifv) | Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen | Descriptor: | PCNA, SODIUM ION | Authors: | Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. | Deposit date: | 2009-07-26 | Release date: | 2009-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Bmc Struct.Biol., 9, 2009
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3VKX
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![BU of 3vkx by Molmil](/molmil-images/mine/3vkx) | Structure of PCNA | Descriptor: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | Authors: | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | Deposit date: | 2011-11-26 | Release date: | 2012-03-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
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2HIK
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![BU of 2hik by Molmil](/molmil-images/mine/2hik) | heterotrimeric PCNA sliding clamp | Descriptor: | PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) | Authors: | Pascal, J.M, Tsodikov, O.V, Ellenberger, T. | Deposit date: | 2006-06-29 | Release date: | 2006-11-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
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2HII
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![BU of 2hii by Molmil](/molmil-images/mine/2hii) | heterotrimeric PCNA sliding clamp | Descriptor: | PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) | Authors: | Pascal, J.M, Tsodikov, O.V, Ellenberger, T. | Deposit date: | 2006-06-29 | Release date: | 2006-11-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
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