3DBX
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![BU of 3dbx by Molmil](/molmil-images/mine/3dbx) | Structure of chicken CD1-2 with bound fatty acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CD1-2 antigen, ... | Authors: | Zajonc, D.M, Wilson, I.A. | Deposit date: | 2008-06-02 | Release date: | 2008-11-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1 Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DHJ
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![BU of 3dhj by Molmil](/molmil-images/mine/3dhj) | Beta 2 microglobulin mutant W60C | Descriptor: | Beta-2-microglobulin | Authors: | Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V. | Deposit date: | 2008-06-18 | Release date: | 2008-11-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DE loop mutations affect beta2-microglobulin stability and amyloid aggregation Biochem.Biophys.Res.Commun., 377, 2008
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2BSS
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![BU of 2bss by Molmil](/molmil-images/mine/2bss) | Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705 | Descriptor: | BETA-2-MICROGLOBULIN, HIV PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN | Authors: | Stewart-Jones, G.B.E, Di Gleria, K, Kollnberger, S, Mcmichael, A.J, Jones, E.Y, Bowness, P. | Deposit date: | 2005-05-23 | Release date: | 2005-05-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705 Eur.J.Immunol., 35, 2005
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3DRQ
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![BU of 3drq by Molmil](/molmil-images/mine/3drq) | Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671 soaked in PEG/2-propanol solution | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, GLYCEROL, ... | Authors: | Bryson, S, Julien, J.P, Pai, E.F. | Deposit date: | 2008-07-11 | Release date: | 2008-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384, 2008
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5V5L
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![BU of 5v5l by Molmil](/molmil-images/mine/5v5l) | |
3RWI
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![BU of 3rwi by Molmil](/molmil-images/mine/3rwi) | Rhesus macaque MHC class I molecule Mamu-B*17-GW10 | Descriptor: | Beta-2-microglobulin, Major histocompatibility complex class I, Vif GW10 peptide from Virion infectivity factor | Authors: | Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. | Deposit date: | 2011-05-09 | Release date: | 2012-03-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
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6Z9V
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![BU of 6z9v by Molmil](/molmil-images/mine/6z9v) | Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | Deposit date: | 2020-06-04 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
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6ULN
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5TR8
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![BU of 5tr8 by Molmil](/molmil-images/mine/5tr8) | Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6. | Descriptor: | 441D6 Fab Heavy chain, 441D6 Fab Light chain, NICKEL (II) ION | Authors: | Joyce, M.G, Kanekiyo, M, Mascola, J.R, Graham, B.S, Kwong, P.D. | Deposit date: | 2016-10-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nat.Immunol., 20, 2019
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5VKK
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3WE6
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![BU of 3we6 by Molmil](/molmil-images/mine/3we6) | |
5EU6
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![BU of 5eu6 by Molmil](/molmil-images/mine/5eu6) | HLA Class I antigen | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | Deposit date: | 2015-11-18 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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7KP1
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![BU of 7kp1 by Molmil](/molmil-images/mine/7kp1) | CD1a-42:2 SM binary complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, T-cell surface glycoprotein CD1a, ... | Authors: | Wegrecki, M, Le Nours, J, Rossjohn, J. | Deposit date: | 2020-11-10 | Release date: | 2021-05-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
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7ZT4
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![BU of 7zt4 by Molmil](/molmil-images/mine/7zt4) | Structure of E8 TCR in complex with human MR1 bound to 6FP | Descriptor: | 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Karuppiah, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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3V7M
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![BU of 3v7m by Molmil](/molmil-images/mine/3v7m) | Crystal structure of monoclonal human anti-Rhesus D Fc IgG1 T125(YB2/0) in the presence of Zn2+ | Descriptor: | GLYCEROL, IMIDAZOLE, Ig gamma-1 chain C region, ... | Authors: | Menez, R, Stura, E.A, Bourel, D, Siberil, S, Jorieux, S, De Romeuf, C, Ducancel, F, Fridman, W.H, Teillaud, J.L. | Deposit date: | 2011-12-21 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Effect of zinc on human IgG1 and its Fc gamma R interactions. Immunol.Lett., 143, 2012
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6AVF
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![BU of 6avf by Molmil](/molmil-images/mine/6avf) | Crystal structure of the KFJ5 TCR-NY-ESO-1-HLA-B*07:02 complex | Descriptor: | ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Gully, B.S, Gras, S, Rossjohn, J. | Deposit date: | 2017-09-02 | Release date: | 2018-02-28 | Last modified: | 2019-04-17 | Method: | X-RAY DIFFRACTION (2.028 Å) | Cite: | Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nat Commun, 9, 2018
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5C0B
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![BU of 5c0b by Molmil](/molmil-images/mine/5c0b) | 1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI | Descriptor: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | Authors: | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | Deposit date: | 2015-06-12 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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5YXN
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6DFX
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![BU of 6dfx by Molmil](/molmil-images/mine/6dfx) | human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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1FE8
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![BU of 1fe8 by Molmil](/molmil-images/mine/1fe8) | CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, IMMUNOGLOBULIN IGG RU5, ... | Authors: | Bouma, B, Huizinga, E.G, Schiphorst, M.E, Sixma, J.J, Kroon, J, Gros, P. | Deposit date: | 2000-07-21 | Release date: | 2001-04-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Identification of the collagen-binding site of the von Willebrand factor A3-domain. J.Biol.Chem., 276, 2001
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3FON
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![BU of 3fon by Molmil](/molmil-images/mine/3fon) | Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI | Descriptor: | Beta-2-microglobulin, MHC, Peptide | Authors: | Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | Deposit date: | 2008-12-30 | Release date: | 2010-01-12 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int.Immunol., 22, 2010
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5HHN
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![BU of 5hhn by Molmil](/molmil-images/mine/5hhn) | Crystal Structure of HLA-A*0201 in complex with M1-F5L | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Gras, S, Josephs, T.M, Rossjohn, J. | Deposit date: | 2016-01-11 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses. Proc.Natl.Acad.Sci.USA, 113, 2016
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8HSW
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![BU of 8hsw by Molmil](/molmil-images/mine/8hsw) | |
7L1B
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![BU of 7l1b by Molmil](/molmil-images/mine/7l1b) | |
4HAF
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![BU of 4haf by Molmil](/molmil-images/mine/4haf) | Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | Authors: | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | Deposit date: | 2012-09-26 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface. Mol.Immunol., 56, 2013
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