5VKK

Crystal structure of Fab fragment of anti-CD22 Epratuzumab

Summary for 5VKK

Entry DOI	10.2210/pdb5vkk/pdb
Descriptor	Epratuzumab Fab Heavy Chain, Epratuzumab Fab Light Chain (3 entities in total)
Functional Keywords	therapeutic antibody, b cell, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	95590.24
Authors	Sicard, T.,Ereno-Orbea, J.,Julien, J.P. (deposition date: 2017-04-21, release date: 2017-10-04, Last modification date: 2023-10-04)
Primary citation	Ereno-Orbea, J.,Sicard, T.,Cui, H.,Mazhab-Jafari, M.T.,Benlekbir, S.,Guarne, A.,Rubinstein, J.L.,Julien, J.P. Molecular basis of human CD22 function and therapeutic targeting. Nat Commun, 8:764-764, 2017 Cited by PubMed: 28970495 DOI: 10.1038/s41467-017-00836-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.014 Å)

Structure validation