2QRI
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Summary for 2QRI
| Entry DOI | 10.2210/pdb2qri/pdb |
| Related | 2QRS 2QRT |
| Descriptor | H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide (2 entities in total) |
| Functional Keywords | mhc-i, ova, single chain mhc-i, glycoprotein, immune response, membrane, mhc i, transmembrane, immune system |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 94132.74 |
| Authors | Mitaksov, V.E.,Fremont, D.H. (deposition date: 2007-07-28, release date: 2007-11-06, Last modification date: 2023-08-30) |
| Primary citation | Mitaksov, V.,Truscott, S.M.,Lybarger, L.,Connolly, J.M.,Hansen, T.H.,Fremont, D.H. Structural engineering of pMHC reagents for T cell vaccines and diagnostics. Chem.Biol., 14:909-922, 2007 Cited by PubMed: 17719490DOI: 10.1016/j.chembiol.2007.07.010 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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