PDB: 219886 resultsInfo pagesStatus searchChemie searchBIRD

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2O9T	beta-glucosidase B from Bacillus polymyxa complexed with glucose Descriptor: Beta-glucosidase B, beta-D-glucopyranose Authors: Isorna, P, Polaina, J, Sanz-Aparicio, J. Deposit date: 2006-12-14 Release date: 2007-10-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structures of Paenibacillus polymyxa beta-Glucosidase B Complexes Reveal the Molecular Basis of Substrate Specificity and Give New Insights into the Catalytic Machinery of Family I Glycosidases J.Mol.Biol., 371, 2007
1O6L	Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide Descriptor: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D. Deposit date: 2002-10-08 Release date: 2002-11-19 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp Nat.Struct.Biol., 9, 2002
3ZKP	Structure of a mutant of P450 EryK in complex with erythromycin B. Descriptor: ERYTHROMYCIN C-12 HYDROXYLASE, Erythromycin B, PROTOPORPHYRIN IX CONTAINING FE Authors: Montemiglio, L.C, Vallone, B, Savino, C. Deposit date: 2013-01-24 Release date: 2013-05-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Redirecting P450 Eryk Specificity by Rational Site-Directed Mutagenesis. Biochemistry, 52, 2013
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
5WCD	Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 04-1D02 Fab. Descriptor: PHOSPHATE ION, SULFATE ION, VRC315 04-1D02 Fab Heavy chain, ... Authors: Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. Deposit date: 2017-06-29 Release date: 2017-08-23 Last modified: 2018-11-28 Method: X-RAY DIFFRACTION (1.814 Å) Cite: Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
5WCA	Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 27-1C08 Fab. Descriptor: VRC315 27-1C08 Fab Heavy chain, VRC315 27-1C08 Fab Light chain Authors: Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. Deposit date: 2017-06-29 Release date: 2017-08-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.369 Å) Cite: Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4QP8	Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine Descriptor: 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 Authors: Yin, J, Wang, W. Deposit date: 2014-06-22 Release date: 2015-09-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.446 Å) Cite: Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
7INS	STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z Descriptor: GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ... Authors: Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F. Deposit date: 1991-09-03 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of porcine insulin cocrystallized with clupeine Z. Acta Crystallogr.,Sect.B, 47, 1991
3M2R	Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues Descriptor: 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, Coenzyme B, ... Authors: Cedervall, P.E, Dey, M, Ragsdale, S.W, Wilmot, C.M. Deposit date: 2010-03-08 Release date: 2010-09-15 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues. Biochemistry, 49, 2010
5LGK	Crystal structure of the human IgE-Fc bound to its B cell receptor derCD23 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, ... Authors: Dhaliwal, B, Pang, M.O.Y, Sutton, B.J. Deposit date: 2016-07-07 Release date: 2017-04-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.5 Å) Cite: IgE binds asymmetrically to its B cell receptor CD23. Sci Rep, 7, 2017
2OTT	Crystal structure of CD5_DIII Descriptor: T-cell surface glycoprotein CD5 Authors: Rodamilans, B. Deposit date: 2007-02-09 Release date: 2007-03-13 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain. J.Biol.Chem., 282, 2007
4QP7	Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine Descriptor: 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 Authors: Yin, J, Wang, W. Deposit date: 2014-06-22 Release date: 2015-09-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.249 Å) Cite: Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4QPA	Crystal Structure of ERK2 in complex with 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine Descriptor: 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 Authors: Yin, J, Wang, W. Deposit date: 2014-06-22 Release date: 2015-09-23 Last modified: 2015-12-16 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
6CCL	Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 1-benzyl-1H-imidazo[4,5-b]pyridine Descriptor: 1-benzyl-1H-imidazo[4,5-b]pyridine, DIMETHYL SULFOXIDE, Phosphopantetheine adenylyltransferase, ... Authors: Mamo, M, Appleton, B.A. Deposit date: 2018-02-07 Release date: 2018-03-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria. J. Med. Chem., 61, 2018
5UKR	Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab in complex with a gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric B.YU2 gp120 core derived from HIV-1 Env, DH522.2 Fab fragment heavy chain, ... Authors: Nicely, N.I. Deposit date: 2017-01-23 Release date: 2017-12-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.712 Å) Cite: Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017
4I7F	HIV-1 Reverse Transcriptase in complex with a phosphonate analog of nevirapine Descriptor: CHLORIDE ION, MAGNESIUM ION, Reverse transcriptase, ... Authors: Lansdon, E.B, Parrish, J. Deposit date: 2012-11-30 Release date: 2013-02-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Synthesis and biological evaluation of phosphonate analogues of nevirapine. Bioorg.Med.Chem.Lett., 23, 2013
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
6CT2	MYST histone acetyltransferase KAT6A/B in complex with WM-1119 Descriptor: 3-fluoro-N'-[(2-fluorophenyl)sulfonyl]-5-(pyridin-2-yl)benzohydrazide, Histone acetyltransferase KAT8, MAGNESIUM ION, ... Authors: Ren, B, Peat, T.S. Deposit date: 2018-03-22 Release date: 2018-08-01 Last modified: 2018-08-22 Method: X-RAY DIFFRACTION (2.128 Å) Cite: Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature, 560, 2018
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
3LN4	Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2 Descriptor: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ... Authors: Theodossis, A, Gras, S, Rossjohn, J. Deposit date: 2010-02-01 Release date: 2010-10-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.296 Å) Cite: The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
3GZX	Crystal Structure of the Biphenyl Dioxygenase in complex with Biphenyl from Comamonas testosteroni Sp. Strain B-356 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BIPHENYL, Biphenyl dioxygenase subunit alpha, ... Authors: Kumar, P, Colbert, C.L, Bolin, J.T. Deposit date: 2009-04-08 Release date: 2010-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes Plos One, 8, 2013
1XWW	Crystal Structure of Human B-form Low Molecular Weight Phosphotyrosyl Phosphatase at 1.6 Angstrom Resolution Descriptor: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION Authors: Stauffacher, C.V, Zabell, A.P.R. Deposit date: 2004-11-02 Release date: 2005-11-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Crystal structure of the human B-form low molecular weight phosphotyrosyl phosphatase at 1.6-A resolution. J.Biol.Chem., 281, 2006
2PGY	GTB C209A, no Hg Descriptor: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase Authors: Letts, J.A, Schuman, B. Deposit date: 2007-04-10 Release date: 2007-07-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.39 Å) Cite: The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B. Acta Crystallogr.,Sect.D, 63, 2007
5U3L	Crystal Structure of DH511.2 Fab in Complex with HIV-1 gp41 MPER 670-683 Peptide Descriptor: DH511.2 Fab Heavy Chain, DH511.2 Fab Light Chain, gp41 MPER peptide Authors: Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. Deposit date: 2016-12-02 Release date: 2017-02-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.165 Å) Cite: Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

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