1FOS
 
 | | TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES | | Descriptor: | C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ... | | Authors: | Glover, J.N.M, Harrison, S.C. | | Deposit date: | 1995-03-07 | | Release date: | 1995-07-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Nature, 373, 1995
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1I8G
 | | SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH CDC25 PHOSPHOTHREONINE PEPTIDE | | Descriptor: | M-PHASE INDUCER PHOSPHATASE 3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | | Authors: | Wintjens, R, Wieruszeski, J.-M, Drobecq, H, Lippens, G, Landrieu, I. | | Deposit date: | 2001-03-14 | | Release date: | 2001-07-18 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | 1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides.
J.Biol.Chem., 276, 2001
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1D66
 | | DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX | | Descriptor: | CADMIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), ... | | Authors: | Marmorstein, R, Carey, M, Ptashne, M, Harrison, S.C. | | Deposit date: | 1992-03-06 | | Release date: | 1992-03-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | DNA recognition by GAL4: structure of a protein-DNA complex.
Nature, 356, 1992
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7KDZ
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3RJR
 | | Crystal Structure of pro-TGF beta 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1 | | Authors: | Zhu, J.H, Shi, M.L, Springer, T.A. | | Deposit date: | 2011-04-15 | | Release date: | 2011-06-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Latent TGF-Beta structure and activation
Nature, 474, 2011
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1BUH
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3MHR
 | | 14-3-3 sigma in complex with YAP pS127-peptide | | Descriptor: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C. | | Deposit date: | 2010-04-08 | | Release date: | 2010-09-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution
Acta Crystallogr.,Sect.F, 66, 2010
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1KQQ
 | | Solution Structure of the Dead ringer ARID-DNA Complex | | Descriptor: | 5'-D(*CP*CP*AP*CP*AP*TP*CP*AP*AP*TP*AP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*TP*AP*TP*TP*GP*AP*TP*GP*TP*GP*G)-3', DEAD RINGER PROTEIN | | Authors: | Iwahara, J, Iwahara, M, Daughdrill, G.W, Ford, J, Clubb, R.T. | | Deposit date: | 2002-01-07 | | Release date: | 2002-03-06 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.
EMBO J., 21, 2002
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1BLX
 | | P19INK4D/CDK6 COMPLEX | | Descriptor: | CALCIUM ION, CYCLIN-DEPENDENT KINASE 6, P19INK4D | | Authors: | Brotherton, D.H, Dhanaraj, V, Wick, S, Brizuela, L, Domaille, P.J, Volyanik, E, Xu, X, Parisini, E, Smith, B.O, Archer, S.J, Serrano, M, Brenner, S.L, Blundell, T.L, Laue, E.D. | | Deposit date: | 1998-07-21 | | Release date: | 1999-06-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
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1FMM
 | | SOLUTION STRUCTURE OF NFGF-1 | | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | | Authors: | Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. | | Deposit date: | 2000-08-18 | | Release date: | 2001-08-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens.
J.Biol.Chem., 277, 2002
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7JT4
 | | Crystal Structure of BPTF bromodomain labelled with 5-fluoro-tryptophan | | Descriptor: | Nucleosome-remodeling factor subunit BPTF | | Authors: | Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | | Deposit date: | 2020-08-17 | | Release date: | 2021-07-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor
Org.Biomol.Chem., 17, 2019
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1DI8
 | | THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE | | Descriptor: | 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, CYCLIN-DEPENDENT KINASE 2 | | Authors: | Shewchuk, L, Hassell, A, Kuyper, L.F. | | Deposit date: | 1999-11-29 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase.
J.Med.Chem., 43, 2000
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2PHI
 | | A LARGE CONFORMATIONAL CHANGE IS FOUND IN THE CRYSTAL STRUCTURE OF THE PORCINE PANCREATIC PHOSPHOLIPASE A2 POINT MUTANT F63V | | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | | Authors: | Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J. | | Deposit date: | 1993-04-08 | | Release date: | 1993-07-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
J.Mol.Biol., 232, 1993
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7JPN
 | | Cryo-EM structure of Arpin-bound Arp2/3 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | Authors: | van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G. | | Deposit date: | 2020-08-09 | | Release date: | 2022-02-09 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
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1FL7
 | | HUMAN FOLLICLE STIMULATING HORMONE | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE STIMULATING PROTEIN ALPHA CHAIN, ... | | Authors: | Fox, K.M, Dias, J.A, Van Roey, P. | | Deposit date: | 2000-08-11 | | Release date: | 2001-03-14 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Three-dimensional structure of human follicle-stimulating hormone.
Mol.Endocrinol., 15, 2001
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1FLI
 | | DNA-BINDING DOMAIN OF FLI-1 | | Descriptor: | FLI-1 | | Authors: | Liang, H, Mao, X, Olejniczak, E.T, Nettesheim, D.G, Yu, L, Meadows, R.P, Thompson, C.B, Fesik, S.W. | | Deposit date: | 1994-09-15 | | Release date: | 1995-09-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the ets domain of Fli-1 when bound to DNA.
Nat.Struct.Biol., 1, 1994
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1HOM
 | | DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | | Descriptor: | ANTENNAPEDIA PROTEIN | | Authors: | Qian, Y.-Q, Billeter, M, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | | Deposit date: | 1991-10-08 | | Release date: | 1993-10-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 214, 1990
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2P2T
 | | Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74 | | Descriptor: | ACETATE ION, Dynein intermediate chain peptide, Dynein light chain 1, ... | | Authors: | Benison, G, Karplus, P.A, Barbar, E. | | Deposit date: | 2007-03-07 | | Release date: | 2008-01-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site.
J.Mol.Biol., 371, 2007
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3L1S
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1HNE
 | | Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-angstroms resolution | | Descriptor: | HUMAN LEUCOCYTE ELASTASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALA CHLOROMETHYL KETONE INHIBITOR | | Authors: | Navia, M.A, Mckeever, B.M, Springer, J.P, Lin, T.-Y, Williams, H.R, Fluder, E.M, Dorn, C.P, Hoogsteen, K. | | Deposit date: | 1989-04-10 | | Release date: | 1989-10-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.
Proc.Natl.Acad.Sci.USA, 86, 1989
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1J2C
 | | Crystal structure of rat heme oxygenase-1 in complex with biliverdin IXalpha-iron cluster | | Descriptor: | BILIVERDINE IX ALPHA, FE (III) ION, Heme Oxygenase-1 | | Authors: | Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K. | | Deposit date: | 2002-12-29 | | Release date: | 2003-09-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Rat Heme Oxygenase-1 in Complex with Biliverdin-Iron Chelate: CONFORMATIONAL CHANGE OF THE DISTAL HELIX DURING THE HEME CLEAVAGE REACTION.
J.Biol.Chem., 278, 2003
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1L0O
 | | Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ... | | Authors: | Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A. | | Deposit date: | 2002-02-12 | | Release date: | 2002-04-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF.
Cell(Cambridge,Mass.), 108, 2002
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1IRM
 | | Crystal structure of apo heme oxygenase-1 | | Descriptor: | apo heme oxygenase-1 | | Authors: | Sugishima, M, Sakamoto, H, Kakuta, Y, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K. | | Deposit date: | 2001-10-09 | | Release date: | 2002-07-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of rat apo-heme oxygenase-1 (HO-1): mechanism of heme binding in HO-1 inferred from structural comparison of the apo and heme complex forms
Biochemistry, 41, 2002
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3NUX
 | | CDK6 (monomeric) in complex with inhibitor | | Descriptor: | 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine, Cell division protein kinase 6 | | Authors: | Chopra, R. | | Deposit date: | 2010-07-07 | | Release date: | 2010-12-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
J.Med.Chem., 53, 2010
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1IVJ
 | | Crystal Structure of Rat Hemeoxygenase-1 in Complex with Heme and Azide. | | Descriptor: | AZIDE ION, Hemeoxygenase-1, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K. | | Deposit date: | 2002-03-18 | | Release date: | 2002-12-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide. IMPLICATION FOR REGIOSPECIFIC HYDROXYLATION OF HEME AT THE alpha -MESO CARBON
J.Biol.Chem., 277, 2002
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